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Investigation of Magnesium Incorporation Within Gelatin/Calcium Phosphate Nanocomposite Scaffold for Bone Tissue Engineering Publisher



Baheiraei N1 ; Azami M1 ; Hosseinkhani H2
Authors
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Authors Affiliations
  1. 1. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, 1417755469, Iran
  2. 2. Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan

Source: International Journal of Applied Ceramic Technology Published:2015


Abstract

In this study, diffusional method was used to prepare a calcium phosphate/gelatin nanocomposite as a scaffold for bone tissue repair. Incorporation of magnesium (Mg) into mineral phase of the scaffold was also investigated. Addition of Mg ions to the synthesis process caused formation of magnesium phosphate (MgP) and hydroxyapatite (HAp). However, analyses data for the sample lacking Mg showed that the mineral formed within GEL had a low crystalline nature, consisting of HAp and octacalcium phosphate (OCP). With addition of Mg within the structure of precipitated minerals, morphology of minerals was dramatically changed toward being irregular and less ordered. © 2013 The American Ceramic Society.