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Nationwide Prevalence of Diabetes and Prediabetes and Associated Risk Factors Among Iranian Adults: Analysis of Data From Persian Cohort Study Publisher



Khamseh ME1 ; Sepanlou SG2 ; Hashemimadani N1 ; Joukar F3 ; Mehrparvar AH4 ; Faramarzi E5 ; Okatialiabad H6 ; Rahimi Z7 ; Rezaianzadeh A8 ; Homayounfar R9 ; Moradpour F10 ; Valizadeh N11 ; Kheirandish M12 ; Zaboli E13 Show All Authors
Authors
  1. Khamseh ME1
  2. Sepanlou SG2
  3. Hashemimadani N1
  4. Joukar F3
  5. Mehrparvar AH4
  6. Faramarzi E5
  7. Okatialiabad H6
  8. Rahimi Z7
  9. Rezaianzadeh A8
  10. Homayounfar R9
  11. Moradpour F10
  12. Valizadeh N11
  13. Kheirandish M12
  14. Zaboli E13
  15. Moslem A14
  16. Ahmadi A15, 16
  17. Hamzeh B17
  18. Harooni J18
  19. Pourfarzi F19
  20. Abolghasemi MR20
  21. Safarpour AR21
  22. Aminisani N22
  23. Mohammadi Z23
  24. Eghtesad S23
  25. Poustchi H23
  26. Malekzadeh R24
Show Affiliations
Authors Affiliations
  1. 1. Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
  2. 2. Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
  4. 4. Industrial Diseases Research Centre, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  5. 5. Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  6. 6. Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
  7. 7. Department of Biostatistics and Epidemiology, Hearing Research Center, School of Public Health, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  8. 8. Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  9. 9. Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran
  10. 10. Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
  11. 11. Maternal and Child Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran
  12. 12. Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  13. 13. Gastrointestinal Cancer Research Center, Non-Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
  14. 14. Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran
  15. 15. Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
  16. 16. Epidemiology and Biostatistics Department, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
  17. 17. Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
  18. 18. Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
  19. 19. Digestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran
  20. 20. Non-Communicable Research Center, Clinical Forensic Medicine and Toxicology Specialist, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  21. 21. Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  22. 22. Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran
  23. 23. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  24. 24. Digestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, N. Karegar Ave, Tehran, 14117-13014, Iran

Source: Diabetes Therapy Published:2021


Abstract

Introduction: Over the past decades prevalence of diabetes has increased in Iran and other countries. This study aimed to update the prevalence of diabetes and prediabetes in Iran and to determine associated sociodemographic risk factors, as well as diabetes awareness and control. Methods: This is a nationally representative cross-sectional survey that included 163,770 Iranian adults aged 35–70 years, from different ethnic backgrounds, between 2014 and 2020. Diabetes was diagnosed at fasting blood sugar of ≥ 6.99 mmol/L (126 mg/dL), or receiving blood glucose-lowering treatment. Multivariable logistic regression was applied to detect determinants associated with prevalence of diabetes and prediabetes, as well as predictors of diabetes awareness and glycemic control. Results: Sex- and age-standardized prevalence of diabetes and prediabetes was 15.0% (95% CI 12.6–17.3) and 25.4% (18.6–32.1), respectively. Among patients with diabetes, 79.6% (76.2–82.9) were aware of their diabetes. Glycemic control was achieved in 41.2% (37.5–44.8) of patients who received treatment. Older age, obesity, high waist to hip ratio (WHR), and specific ethnic background were associated with a significant risk of diabetes and prediabetes. Higher awareness of diabetes was observed in older patients, married individuals, those with high WHR, and individuals with high wealth score. Moreover, glycemic control was significantly better in women, obese individuals, those with high physical activity, educational attainment, and specific ethnic background. Conclusions: The prevalence of diabetes and prediabetes is increasing at an alarming rate in Iranian adults. High proportion of uncontrolled patients require particular initiatives to be integrated in the health care system. © 2021, The Author(s).
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