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A Comparison Between Electron Gamma Shower, National Research Council/Easy Particle Propagation (Egsnrc/Epp) and Monte Carlo N-Particle Transport Code (Mcnp) in Simulation of the Intrabeam ® System With Spherical Applicators Publisher



Tegaw EM1, 2 ; Geraily G1, 3 ; Etesami SM4 ; Gholami S1, 3 ; Ghanbari H5 ; Farzin M3, 6 ; Tadesse GF1, 7 ; Shojaei M1
Authors
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Authors Affiliations
  1. 1. Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, International Campus (TUMS-IC), Teh-ran, Iran
  2. 2. Department of Physics, Faculty of Natural and Computational Sciences, Debre Tabor University, Debre Tabor, Ethiopia
  3. 3. Radiation Oncology Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Particles and Accelerators, Institute for Research in Funda-mental Sciences (IPM), Tehran, Iran
  5. 5. Department of Medical Nanotechnol-ogy, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Physics, College of Natural and Computational Sciences, Aksum University, Ethiopia

Source: Journal of Biomedical Physics and Engineering Published:2021


Abstract

Background: Online Monte Carlo (MC) treatment planning is very crucial to increase the precision of intraoperative radiotherapy (IORT). However, the performance of MC methods depends on the geometries and energies used for the problem under study. Objective: This study aimed to compare the performance of MC N-Particle Transport Code version 4c (MCNP4c) and Electron Gamma Shower, National Research Council/easy particle propagation (EGSnrc/Epp) MC codes using similar geometry of an INTRABEAM® system. Material and Methods: This simulation study was done by increasing the number of particles and compared the performance of MCNP4c and EGSnrc/Epp simulations using an INTRABEAM® system with 1.5 and 5 cm diameter spherical applicators. A comparison of these two codes was done using simulation time, statistical uncertainty, and relative depth-dose values obtained after doing the simulation by each MC code. Results: The statistical uncertainties for the MCNP4c and EGSnrc/Epp MC codes were below 2% and 0.5%, respectively. 1e9 particles were simulated in 117.89 hours using MCNP4c but a much greater number of particles (5e10 particles) were simulated in a shorter time of 90.26 hours using EGSnrc/Epp MC code. No significant deviations were found in the calculated relative depth-dose values for both in the presence and absence of an air gap between MCNP4c and EGSnrc/Epp MC codes. Nevertheless, the EGSnrc/ Epp MC code was found to be speedier and more efficient to achieve accurate statistical precision than MCNP4c. Conclusion: Therefore, in all comparisons criteria used, EGSnrc/Epp MC code is much better than MCNP4c MC code for simulating an INTRABEAM® system. © 2021, Shriaz University of Medical Sciences. All rights reserved.
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