Tehran University of Medical Sciences

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Issues With Incorrect Computing of Population Attributable Fraction (Paf) in a Global Perspective on Coal-Fired Power Plants and Burden of Lung Cancer Publisher Pubmed



Khosravi A1 ; Mansournia MA2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Epidemiology, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran
  2. 2. Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran

Source: Environmental Health: A Global Access Science Source Published:2019


Abstract

All observational studies are liable to confounding and Levin's formula becomes useless in practice for unbiasedly estimating PAF. With respect to causal interpretation of PAF in public health setting, unbiased estimation of PAF requires several assumptions which are ignored in practice. We recommend using Miettinen PAF formula with careful consideration about possibility of bias in study design and analysis. © 2019 The Author(s).