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Synthesis of Quinazolin-4(3H)-Ones Via the Reaction of Isatoic Anhydride With Benzyl Azides in the Presence of Potassium Tert-Butoxide in Dmso Publisher



Sayahi MH1 ; Bahadorikhalili S2 ; Mahdavi M3 ; Baghshirin L1
Authors
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Authors Affiliations
  1. 1. Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Chemistry of Heterocyclic Compounds Published:2019


Abstract

[Figure not available: see fulltext.] In this paper, a novel method is described for the synthesis of quinazolin-4(3H)-one derivatives via the reaction of isatoic anhydride with benzyl azides in the presence of potassium tert-butoxide in DMSO. The reaction is completed after 4 h at 100°C to produce the title products in good yields. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.