Post–Myocardial Infarction Ventricular Septal Defect Percutaneous Closure Publisher



Jha S ; Soltani P ; Almanfi A
Source: JACC: Case Reports Published:2026

Abstract

Background: Ventricular septal rupture is an uncommon but serious complication of late post–myocardial infarctions (MI) with an exceedingly high mortality. The American College of Cardiology and American Heart Association still advise immediate surgical closure of ventricular septal rupture. Case Summary: We described a novel minimally invasive transcatheter approach to post-MI ventricular septal defect (PMIVSD) closure through a venovenous loop for an 82-year-old woman. Discussion: A PMIVSD is typically treated surgically and offers reasonable outcomes in patients who survive an initial healing phase. Transcatheter approaches serve as a potential treatment option for select high-risk surgical candidates. Take-Home Messages: Transcatheter closure is a viable alternative in high-risk PMIVSD patients unsuitable for surgery. A venovenous loop offers a safe and effective route for percutaneous VSD closure. © 2026 The Authors