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Acute Disseminated Encephalomyelitis; a Rare Iranian Case Report Publisher



Hosseininejad SM1 ; Hosseininejad FS2 ; Salimikordasiabi A1 ; Tabatabaei FS3 ; Derakhshanpour F4 ; Bazrafshan B5 ; Moein M6
Authors
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Authors Affiliations
  1. 1. Golestan University of Medical Sciences, Gorgan, Iran
  2. 2. Shahrood University of Medical Sciences, Shahrood, Iran
  3. 3. Golestan Pediatric and Neonatal Research Center, Golestan University of Medical Sciences, Gorgan, Iran
  4. 4. Golestan Psychiatric Research Center, Golestan University of Medical Sciences, Gorgan, Iran
  5. 5. Medical Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran
  6. 6. Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Pediatrics Published:2017


Abstract

Acute disseminated encephalomyelitis (ADEM) is a monophasic clinical syndrome, characterized by immune-mediated demyelination of central nervous system neurons, which yield extensive damage in the brain and spinal cord. It usually affects children and young adults following infections or immunization. Here we describe a 9- year-old Fars female presented with acute onset of psychotic disorder, one week after an upper respiratory infection. Magnetic resonance images (MRI) of the brain were consistent with the diagnosis of the acute disseminated encephalomyelitis (ADEM). ADEM is one of the differential diagnoses to be considered when an acute psychotic disorder arises during childhood especially as post vaccination or infection.