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Application of Maggot Debridement Therapy on Infected Wounds of Newborns: A Case Series in Iran Publisher



Motallemzadeh S1 ; Tabaie SM2 ; Mirzaei J3 ; Akbarzadeh K4 ; Djavid GE5 ; Sabo YM6 ; Yusuf MA4, 6 ; Malekian A7
Authors
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Authors Affiliations
  1. 1. Nursing of School, Urmia University of Medical Sciences, Urmia, Iran
  2. 2. Medical Laser Research Center, YARA Institute, ACECR, Tehran, Iran
  3. 3. Infectious Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Photo Repair Research Group, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran
  6. 6. Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, Bayero University, Kano, Nigeria
  7. 7. Pasteur Institute of Iran, Tehran, Iran

Source: Nigerian Journal of Basic and Clinical Sciences Published:2023


Abstract

Neonates hospitalized in the Neonatal Intensive Care Units (NICU) are exposed to a higher risk of iatrogenic skin lesions. Maggot Debridement Therapy (MDT) in recent years has gotten more attention as a debriding, and disinfecting agent. The aim of this study was to treat infants with infected wounds and to evaluate the effectiveness and safety of MDT on in this group of patients. The study was conducted on four infants (12 to 30 days old) with infected wounds who could not withstand surgical debridement. Lucilia sericata larvae were used along with other standard therapies. The result of this study showed that MDT is an effective biological debridement tool with a good safety margin amongst infants. It removes all the necrotic tissue and induced granulation after application. In addition, it shortens the healing time, reduced pain, and decreased the rate of antibiotic consumption thereby reducing the overall cost of management. © 2023 Nigerian Journal of Basic and Clinical Sciences.
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1. Sterilization of Lucilia Sericata (Diptera: Calliphoridae) Eggs for Maggot Debridement Therapy, Journal of Medical Entomology (2022)