The Relationship Between Volumetric Assessment of Cleft Lip and Palate Defects With Age Using Cone Beam Computed Tomography



Sayahpour B¹ ; Darnahal A² ; Eslami S³ ; Fazeli D⁴ ; Dolatshahizand H⁴ ; Nahavandi SR⁵ ; Rad APP⁶ ; Jamilian A⁴ Show Affiliations
Source: Journal of Biological Regulators and Homeostatic Agents Published:2022

Abstract

Aim: The aim of this study was to evaluate the Relationship between volumetric assessment of unilateral cleft lip and palate (UCLP) with age in subjects using computed tomography. Materials and methods: This retrospective study consisted of CBCT scans of 96 non-syndromic UCLP patients 52 boys and 44 girls between 7 to 15 years old. The patients with the following criteria were excluded from the study: previous orthodontic treatment, alveolar grafting, orthognathic surgery, trauma, syndromes, history of tonsillectomy, and adenoidectomy. Patients were classified into 4 groups according to their age with approximately equal samples. Materialize Mimics innovation suite 20 software (Leuven, Belgium) was used to measure the maximum diameter of defect in the axial, coronal, sagittal plane in mm, bone defect volume in mm3, and also nasal floor deficiency area, alveolar deficiency area in mm2. Kruskal Wallis test was used to analyze the data. Results: The Maximum diameter of cleft in the sagittal aspect was 39.2±24.6 mm in the 7 till 8 age group and 26.1±10.9 mm in the 13 till 15 years old age group in both genders. There was a reverse significant relationship between age and the maximum diameter of cleft P<0001. There was not any significant relation between defect volume and age. Conclusions: There was not any significant relation between defect volume and age. However, CBCT imaging can be used to assess the volume of the clefts and thus evaluate the amount of bone necessary to repair the cleft area for each age. © by BIOLIFE, s.a.s.