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Improved Diagnostic Accuracy for Myocardial Perfusion Imaging Using Artificial Neural Networks on Different Input Variables Including Clinical and Quantification Data; [Precision Diagnostica Mejorada Para La Imagen De Perfusion Miocardica Usando Redes Neuronales Artificiales En Diferentes Variables De Entrada Incluyendo Datos Clinicos Y De Cuantificacion] Publisher Pubmed



Rahmani R1 ; Niazi P2 ; Naseri M2 ; Neishabouri M2 ; Farzanefar S2 ; Eftekhari M3 ; Derakhshan F2 ; Mollazadeh R1 ; Meysami A4 ; Abbasi M2
Authors
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Authors Affiliations
  1. 1. Cardiology Department, Imam-Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Nuclear Medicine, Vali-asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Research Institute for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Social Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Revista Espanola de Medicina Nuclear e Imagen Molecular Published:2019


Abstract

Objective: Diagnostic accuracy of myocardial perfusion imaging (MPI) is not optimal to predict the result of angiography. The current study aimed at investigating the application of artificial neural network (ANN) to integrate the clinical data with the result and quantification of MPI. Methods: Out of 923 patients with MPI, 93 who underwent angiography were recruited. The clinical data including the cardiac risk factors were collected and the results of MPI and coronary angiography were recorded. The quantification of MPI polar plots (i.e. the counts of 20 segments of each stress and rest polar plots) and the Gensini score of angiographies were calculated. Feed-forward ANN was designed integrating clinical and quantification data to predict the result of angiography (normal vs. abnormal), non-obstructive or obstructive coronary artery disease (CAD), and Gensini score (≥10 and <10). The ANNs were designed to predict the results of angiography using different combinations of data as follows: reports of MPI, the counts of 40 segments of stress and rest polar plots, and the count of these 40 segments in addition to age, gender, and the number of risk factors. The diagnostic performance of MPI with different ANNs was compared. Results: The accuracy of MPI to predict the result of angiography, obstructive CAD, and Gensini score increased from 81.7% to 92.9%, 65.0% to 85.7%, and 50.5% to 92.9%, respectively by ANN using counts and clinical risk factors. Conclusion: The diagnostic accuracy of MPI could be improved by ANN, using clinical and quantification data. © 2019 Sociedad Espanola de Medicina Nuclear e Imagen Molecular