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Current Trends in Targeted Therapy for Drug-Resistant Infections Publisher Pubmed



Rahbarnia L1 ; Farajnia S2 ; Naghili B1 ; Ahmadzadeh V2 ; Veisi K3, 4 ; Baghban R5 ; Toraby S6
Authors
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Authors Affiliations
  1. 1. Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Drug Applied Research Center, Tabriz University of Medical Sciences, P.O. Box: 51656-65811, Tabriz, Iran
  3. 3. Department of Medical Biotechnology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
  4. 4. Biotechnology Department, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  6. 6. Immunology Research Center, Tabriz, University of Medical Sciences, Tabriz, Iran

Source: Applied Microbiology and Biotechnology Published:2019


Abstract

Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of “postantibiotic age” in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to combat antibiotic-resistant infections. This review focuses on recent advances in this area including therapeutic antibodies, antimicrobial peptides, vaccines, gene therapy, genome editing, and phage therapy for tackling drug-resistant infections. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
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