Environmental Risk Factors of Conduct Disorder: An Overview of Meta-Analyses Publisher



Salmanian M ; Bordbari AH ; Mousavi N ; Tamannaeifar S ; Golzar MH ; Amiri M ; Kargarsoleimanabad S ; Mollaei A ; Mahdavinoor SMM
Source: Iranian Journal of Psychiatry Published:2025

Abstract

Objective: Conduct disorder is one of the most common disorders of childhood and adolescence. This disorder imposes high costs on the individual, family and community. Understanding the risk factors associated with conduct disorder can provide a comprehensive picture of the disorder. Therefore, the aim of this study is to investigate the risk factors related with conduct disorder. Method: We included meta-analyses that reported one or more risk factors of conduct disorder. We searched PubMed and Scopus until July 19, 2025. One author assessed the quality of the included studies using the ROBIS, and two authors extracted relevant data independently. Results: We found 12 articles that met the inclusion criteria, from which data pertaining to 17 meta-analyses were extracted. The risk factors identified by the meta-analyses were as follows: severe psychiatric disorders in parents, postnatal exposure to second-hand smoke, atopic dermatitis, being children of alcoholics, prenatal alcohol exposure, maternal smoking during pregnancy, maternal alcohol use during pregnancy, overweight/obesity, maternal perinatal depression, preconception overweight, and preconception obesity. Conclusion: Drawing on 17 meta-analyses, this study provides a comprehensive synthesis of the risk factors associated with conduct disorder. The findings can inform policymakers and healthcare professionals to develop targeted interventions, such as public health campaigns and support programs for at-risk families, to mitigate these risks. Furthermore, this study highlights the gaps in the existing literature, including the reliance on older studies and methodological limitations, paving the way for future research to address these shortcomings and strengthen the evidence base. © 2025 Elsevier B.V., All rights reserved.