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Unilateral Generalized Morphea: A Case Report and Literature Review



Nasimi M1 ; Azizpour A1, 2 ; Abedini R1 ; Ghanadan A3
Authors
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Authors Affiliations
  1. 1. Department of Dermatology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Pathology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Dermatology Published:2017

Abstract

Morphea is an autoimmune connective tissue disease of the dermis and subcutaneous fat characterized by sclerosis due to excessive collagen deposition. Morphea is classified into different subtypes based on clinical and histological characteristics of cutaneous lesions. An extremely rare subtype of morphea is termed unilateral generalized morphea (UGM). UGM is characterized by indurated plaques on dermatomes of the trunk or back with a sharp midline demarcation line. Ipsilateral limbs may also be affected. There is still debate on whether this type of morphea should be considered as a distinct type or a presentation of linear morphea. Here we report the case of an 8-year-old boy with this type of morphea. © 2018, Iranian Society of Dermatology. All rights reserved.