Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Effects of Pomegranate Juice Consumption on Oxidative Stress in Patients With Type 2 Diabetes: A Single-Blind, Randomized Clinical Trial Publisher Pubmed



Sohrab G1 ; Ebrahimof S2 ; Sotoudeh G3 ; Neyestani TR4 ; Angoorani P2 ; Hedayati M5 ; Siasi F3
Authors

Source: International Journal of Food Sciences and Nutrition Published:2017


Abstract

Increased free radicals production due to hyperglycemia produces oxidative stress in patients with diabetes. Pomegranate juice (PJ) has antioxidant properties. This study was conducted to determine the effects of PJ consumption in oxidative stress in type 2 diabetic patients. This study was a randomized clinical trial performed on 60, 40–65 years old diabetic patients. The patients were randomly allocated either to PJ consumption group or control. Patients in PJ group consumed 200 ml of PJ daily for six weeks. Sex distribution and the mean age were not different between two groups. After six weeks intervention, oxidized LDL and anti-oxidized LDL antibodies decreased and total serum antioxidant capacity and arylesterase activity of paraoxonase increased significantly in the PJ-treated group compared to the control group. Our data have shown that six weeks supplementation of PJ could have favorable effects on oxidative stress in patients with type 2 diabetes (T2D). © 2016 Informa UK Limited, trading as Taylor & Francis Group.
Related Docs
View other Related Docs
1. The Power of Punica Granatum: A Natural Remedy for Oxidative Stress and Inflammation; a Narrative Review, Journal of Ethnopharmacology (2024)
2. Effects of Pomegranate Juice Consumption on Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes: A Single-Blind Randomized Clinical Trial, Clinical Nutrition ESPEN (2019)
3. The Effect of Pomegranate (Punica Granatum) Supplementation on Metabolic Status in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis, Complementary Therapies in Medicine (2020)
Experts (# of related papers)
View all Related Experts
Mehdi Yaseri (2)
Mohammad Hassan Javanbakht (2)
Other Related Docs
4. The Effect of Pomegranate on Oxidative Stress Parameters: A Systematic Review and Meta-Analysis, Complementary Therapies in Medicine (2020)
5. Is Consumption of Pomegranate Supplementation Effective on Oxidative Stress Biomarkers Including Mda, Ox-Ldl, Pox 1, Gpx, Tac, and Tbras? a Systematic Review and Meta-Analysis of Randomized Controlled Trials, Current Problems in Cardiology (2023)
6. Effects of Pomegranate and Orange Juice on Antioxidant Status in Non-Alcoholic Fatty Liver Disease Patients: A Randomized Clinical Trial, International Journal for Vitamin and Nutrition Research (2015)
7. The Effect of Eicosapentaenoic Acid on the Serum Levels and Enzymatic Activity of Paraoxonase 1 in the Patients With Type 2 Diabetes Mellitus, Acta Medica Iranica (2017)
8. Bioactive Foods and Medicinal Plants for Cardiovascular Complications of Type Ii Diabetes: Current Clinical Evidence and Future Perspectives, Evidence-based Complementary and Alternative Medicine (2021)
9. The Effect of Cold Plasma on Antioxidant Enzymes, Minerals, and Some of the Levels of the Biochemical Parameters in the Subjects With Type 2 Diabetes Mellitus Samples, Bioactive Compounds in Health and Disease (2021)
10. Interaction Between Apo A-Ii -265T > C Polymorphism and Dietary Total Antioxidant Capacity on Some Oxidative Stress and Inflammatory Markers in Patients With Type 2 Diabetes Mellitus, British Journal of Nutrition (2022)
11. Effects of Pomegranate Extract Supplementation on Inflammation in Overweight and Obese Individuals: A Randomized Controlled Clinical Trial, Complementary Therapies in Clinical Practice (2016)
12. Oxidized Low-Density Lipoprotein (Ox-Ldl) to Ldl Ratio (Ox-Ldl/Ldl) and Ox-Ldl to High-Density Lipoprotein Ratio (Ox-Ldl/Hdl): Are They Accurate Biomarkers of Type 2 Diabetes Mellitus?, Clinical Laboratory (2016)
13. The Effect of Aqueous, Ethanolic Extracts Ofrheum Ribeson Insulin Sensitivity, Inflammation, Oxidative Stress in Patients With Type 2 Diabetes Mellitus: A Randomized, Double-Blind, Placebo-Controlled Trial, Journal of Herbal Medicine (2020)
14. Effects of Vitamin D Supplementation on 8-Hydroxydeoxy Guanosine and 3-Nitrotyrosine in Patients With Type 2 Diabetes: A Randomized Clinical Trial, Progress in Nutrition (2019)
15. Dietary Total Antioxidant Capacity Can Modify the Effects of Apo-B Polymorphisms (Ins/Del and Ecori) on Lipid Profiles and Atherogenic Indices Between Diabetic Patients, Molecular Nutrition and Food Research (2025)
16. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Tomato and Diabetes, Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease (2015)
17. Does Supplementation With Royal Jelly Improve Oxidative Stress and Insulin Resistance in Type 2 Diabetic Patients?, Iranian Journal of Public Health (2015)
18. Interaction Between the Dietary Indices and Ppar-Γ Pro12ala Gene Variants on Cardiovascular Risk Factors in Patients With Type 2 Diabetes Mellitus, International Journal of Clinical Practice (2021)
19. Antioxidative Effects of Tempol on Mitochondrial Dysfunction in Diabetic Nephropathy, Iranian Journal of Kidney Diseases (2018)
20. Effects of Probiotics and Synbiotic Supplementation on Antioxidant Status: A Meta-Analysis of Randomized Clinical Trials, Clinical Nutrition ESPEN (2019)