Treatment of a Dentigerous Cyst With Autologous Tooth Grafting and Platelet-Rich Plasma: A Case Report Publisher



Escotovasquez LS ; Romerolecanda JA ; Lomelimartinez SM ; Martineznieto M ; Heboyan A ; Alarconsanchez MA
Source: Journal of Surgical Case Reports Published:2026

Abstract

Dentigerous cysts are the second most common odontogenic cysts and are frequently associated with impacted mandibular third molars. Although enucleation remains the standard treatment, regenerative approaches using autologous biomaterials have emerged as promising alternatives. This report describes the management of a mandibular dentigerous cyst in a 43-year-old female using conservative enucleation, autologous tooth-derived graft, and fibrin-rich plasma. Radiographic follow-up demonstrated early bone formation, and histopathology confirmed the diagnosis. The combined use of autologous tooth grafting and platelet concentrates represents a viable regenerative option that supports bone preservation and future rehabilitation. © The Author(s) 2026. Published by Oxford University Press and JSCR Publishing Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.