Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Periodic Hypersomnolence in a Young Female Patient: A Case Report and Literature Review Publisher



Alemohammad ZB1 ; Jamshidi S2 ; Najafi A3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Sleep Breathing Disorders Research Center (SBDRC), Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Center for Research on Occupational Diseases (CROD), Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Egyptian Journal of Neurology# Psychiatry and Neurosurgery Published:2022


Abstract

Background: Kleine–Levin syndrome (KLS) is a disease with periodic hypersomnolence accompanied by abnormal behavior with a rare prevalence in female. Case presentation: Here, we report a young lady with chief complaint of hypersomnolence for 6 years of visits and any history of sleep attack, sleep paralysis, and cataplexy. Polysomnography was performed for the patient. The respiratory disturbance index was normal. In MSLT the patient had two SOREMs with mean sleep latency of 7 min. She was diagnosed as Kleine–Levin syndrome as the sleepiness symptoms had a periodic pattern without other characteristics of central hypersomnolence disorders. The patient did not report behavioral characteristics of KLS reported in previous literature. She improved spontaneously after a while in follow-ups without any further treatment. Conclusions: Although KLS is reported rarely in female gender and there are previous defined behavioral symptoms for this syndrome, periodic pattern of sleepiness should raise this diagnosis after exclusion of other hypersomnolence causes. © 2022, The Author(s).