Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Association of Healthy Eating Index and Its Components With Levels of Fasting Blood Sugar and Lipid Profile in Normoglycemic and Hyperglycemic Individuals Publisher



Moradiani M1 ; Movahedi A2 ; Djazayery A3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Nutrition, Faculty of Medical Sciences and Technologies, Islamic Azad University, Science and Research, Tehran, Iran
  2. 2. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
  3. 3. Department of Nutrition, Science and Research Branch, Tehran University of Medical Sciences, Tehran, Iran

Source: Nutrition and Food Science Published:2024


Abstract

Purpose: This study aims to assess the association of Healthy Eating Index (HEI) with levels of fasting blood sugar (FBS) and lipid profile in normoglycemic and elevated FBS patients. Design/methodology/approach: This case-control study was conducted on 144 participants, namely, 72 normoglycemic subjects (FBS < 100 mg/dl) and 72 high-glycemic patients (FBS ≥ 100 mg/dl) aged 20–60 years of age, who were selected from the nutrition and diet clinics in Tehran city. The dietary intake was collected by using a validated food frequency questionnaire to determine the HEI score. Findings: The mean±SD age and body mass index of participants were 47.1 ± 12.7 years and 29.6 ± 6.0 kg/m2, respectively. The median (interquartile range) of HEI scores in the normoglycemic group and the high-glycemia group were 19.34 (15.24–24.31) and 16.53 (13.35–24.07), respectively. In the overall population, the findings of the multi-variable linear regression model indicated a positive association between the HEI score and high-density lipoprotein-cholesterol (HDL-C) (ß = 0.34; 95%CI: 0.05–0.64, P = 0.01). However, there is no significant association between HEI and HDL-C in normoglycemic (ß = 0.19; 95%CI: −0.31, 0.69, P = 0.45) and hyperglycemic subjects (ß = 0.28; 95%CI: −0.10–0.66, P = 0.15). Furthermore, the association of HEI with levels of FBS, triglycerides (TGs) and low-density lipoprotein-cholesterol (LDL-C) was not significant in any of the analyzed groups, including the total population, normoglycemic individuals and hyperglycemic subjects. Originality/value: This study was the first study to assess the role of HEI and its components with levels of FBS and lipid profile in normoglycemic and hyperglycemic individuals in Iran. The findings suggested that higher adherence to HEI may be associated with an increase in the HDL-C level. However, HEI could not predict FBS, TGs and LDL-C levels in the adult population. © 2024, Emerald Publishing Limited.
Related Docs
View other Related Docs
1. Interactions of Bdnf Val66met and Dietary Indices in Relation to Metabolic Markers Among Patient With Type 2 Diabetes Mellitus: A Cross-Sectional Study, Journal of Health# Population and Nutrition (2023)
2. Diet Quality Indices and Cardiovascular Diseases Risk Factors Among Diabetic Women, Journal of the Science of Food and Agriculture (2019)
3. Association Between Healthy Eating Index-2015 Scores and Metabolic Syndrome Among Iranian Women: A Cross-Sectional Study, BMC Women's Health (2024)
4. Interaction Between Cetp Taq1b Polymorphism and Hei, Dqi and Dpi on Metabolic Biomarkers in Patients With Type 2 Diabetes, Journal of Human Nutrition and Dietetics (2022)
5. The Interaction Between Cry1 Polymorphism and Alternative Healthy Eating Index (Ahei) on Cardiovascular Risk Factors in Overweight Women and Women With Obesity: A Cross-Sectional Study, BMC Endocrine Disorders (2023)
6. The Role of Dietary Glycemic Index and Glycemic Load in Mediating Genetic Susceptibility Via Mc4r S17782313 Genotypes to Affect Cardiometabolic Risk Factors Among Apparently Healthy Obese Individuals, BioMed Research International (2022)
7. A Personalised Diet Approach Study: Interaction Between Ppar-Γ Pro12ala and Dietary Insulin Indices on Metabolic Markers in Diabetic Patients, Journal of Human Nutrition and Dietetics (2022)
8. The Association of Dietary and Lifestyle Indices for Insulin Resistance With the Risk of Cardiometabolic Diseases Among Iranian Adults, Scientific Reports (2023)
Experts (# of related papers)
View all Related Experts
Leila Azadbakht (8)
Khadijeh Mirzaei (4)
Other Related Docs
9. Long-Term Effectiveness of a Lifestyle Intervention on the Prevention of Type 2 Diabetes in a Middle-Income Country, Scientific Reports (2020)
10. Comparison of Food Intake, Physical Activity and Weight in Infertile and Healthy Women Aged 25-40 Years, Iranian Journal of Obstetrics# Gynecology and Infertility (2015)
11. Dietary Total Antioxidant Capacity Interacts With a Variant of Chromosome 5Q13-14 Locus to Influence Cardio-Metabolic Risk Factors Among Obese Adults, Egyptian Journal of Medical Human Genetics (2022)
12. Higher Dietary Acid Load Might Be a Potent Derivative Factor for Multiple Sclerosis: The Results From a Case–Control Study, Nutrients (2023)
13. Bibliometric Overview of the Tehran Lipid and Glucose Study (Tlgs) Publications From 2000 to 2022, Journal of Diabetes and Metabolic Disorders (2024)
14. Association of Dietary Energy Density With Cardiometabolic Risk Factors and Metabolic Syndrome in Tehranian Older Adults, Journal of Cardiovascular and Thoracic Research (2020)
15. Dietary Patterns and Risk of Breast Cancer Among Pre and Post-Menopausal Women: A Case-Control Study in Iran, Journal of Nutrition and Food Security (2022)
16. Association Between Dietary Inflammatory Index and Kidney Function in Elderly Population: Results From a Cross-Sectional Study, Nutrition and Food Science (2019)
17. Association of Quality and Quantity of Macronutrients Intake With Obesity, New Anthropometric Indices, Lipid Accumulation, and Blood Lipid Risk Index in Tehranian Women, Food Science and Nutrition (2024)
18. Diet-Dependent Acid Load and the Risk of Colorectal Cancer and Adenoma: A Case-Control Study, Public Health Nutrition (2021)
19. Associations Between Adherence to Mediterranean Dietary Pattern and Frequency, Duration, and Severity of Migraine Headache: A Cross-Sectional Study, Nutritional Neuroscience (2023)
20. Adherence to Plant-Based Dietary Pattern and Risk of Breast Cancer Among Iranian Women, European Journal of Clinical Nutrition (2021)
21. Is There a Relationship Between 24-Hour Urinary Sodium and Potassium and Mental Health in Migraine Patients?: A Cross-Sectional Study, Medicine (United States) (2022)
22. The Interaction Between Alternative Healthy Eating Index and Mc4r Rs17782313 Gene Variants on Central and General Obesity Indices in Women: A Cross-Sectional Study, Journal of Human Nutrition and Dietetics (2022)
23. Does the Mediterranean Diet Reduce the Odds of Diabetic Nephropathy in Women? a Case–Control Study, Frontiers in Nutrition (2022)
24. Mind Diet Adherence Might Be Associated With a Reduced Odds of Multiple Sclerosis: Results From a Case–Control Study, Neurology and Therapy (2022)
25. The Association Between Dietary Diversity Score and Odds of Nonalcoholic Fatty Liver Disease: A Case-Control Study, European Journal of Gastroenterology and Hepatology (2022)
26. Does Alternative Healthy Eating Index Can Predict the Risk of Prostate Cancer?, Nutrition and Food Science (2020)
27. The Association Between Diet Quality and Chronic Obstructive Pulmonary Disease: A Case-Control Study, BMC Public Health (2023)
28. Global Variation in Diabetes Diagnosis and Prevalence Based on Fasting Glucose and Hemoglobin A1c, Nature Medicine (2023)
29. Apoa2-256T > C Polymorphism Interacts With Healthy Eating Index, Dietary Quality Index-International and Dietary Phytochemical Index to Affect Biochemical Markers Among Type 2 Diabetic Patients, British Journal of Nutrition (2022)
30. Fruit and Vegetable Intake and Odds of Pediatric Migraine, Nutrition and Food Science (2020)
31. Macronutrients and the State of Happiness and Mood in Undergraduate Youth of a Military Training Course, Clinical Nutrition ESPEN (2023)
32. Dietary Glycemic Index and Glycemic Load Mediate the Effect of Cartpt Rs2239670 Gene Polymorphism on Metabolic Syndrome and Metabolic Risk Factors Among Adults With Obesity, BMC Endocrine Disorders (2022)
33. Major Dietary Patterns in Relation to Demographic and Socio-Economic Status and Food Insecurity in Two Iranian Ethnic Groups Living in Urmia, Iran, Public Health Nutrition (2016)
34. Interplay Between Fatty Acid Desaturase2 (Fads2) Rs174583 Genetic Variant and Dietary Antioxidant Capacity: Cardio-Metabolic Risk Factors in Obese Individuals, BMC Endocrine Disorders (2022)
35. Is There a Relationship Between Serum Vitamin D and Semen Parameters? a Cross-Sectional Sample of the Iranian Infertile Men, Basic and Clinical Andrology (2021)
36. A Case-Control Study on Dietary Quality Indices and Glioma, British Journal of Nutrition (2019)
37. The Association Between Dietary Glycemic Index and Cardio-Metabolic Risk Factors in Obese Individuals, BMC Nutrition (2022)
38. Associations Between Dairy Products Consumption and Risk of Type 2 Diabetes: Tehran Lipid and Glucose Study, International Journal of Food Sciences and Nutrition (2015)
39. Higher Health Literacy Score Is Associated With Better Healthy Eating Index in Iranian Adults, Nutrition (2021)
40. The Association Between Dietary Pattern and Weight Status in School-Aged Children: A Cross-Sectional Study, Journal of Comprehensive Pediatrics (2017)
41. Associations Between Mother–Child Dyad Dietary Patterns and Child Anthropometric Measures Among 6-Year-Old Children, European Journal of Pediatrics (2022)
42. The Association Between Adherence to Diet Quality Index and Cardiometabolic Risk Factors in Overweight and Obese Women: A Cross-Sectional Study, Frontiers in Public Health (2023)
43. The Association Between Fasting Blood Sugar and Index of Nutritional Quality in Adult Women, Frontiers in Nutrition (2022)
44. The Association Between Dash Diet Adherence and Cardiovascular Risk Factors, International Journal of Preventive Medicine (2023)
45. Associations of Plant-Based Dietary Patterns With Cardiovascular Risk Factors in Women, Journal of Cardiovascular and Thoracic Research (2022)
46. Adherence to Alternative Healthy Eating Index (Ahei-2010) Is Not Associated With Risk of Stroke in Iranian Adults: A Case-Control Study, International Journal for Vitamin and Nutrition Research (2021)
47. Association Between Plant and Animal Proteins Intake With Lipid Profile and Anthropometric Indices: A Cross-Sectional Study, Nutrition and Health (2024)
48. Interaction Between Cetp Polymorphism and Dietary Insulin Index and Load in Relation to Cardiovascular Risk Factors in Diabetic Adults, Scientific Reports (2021)