Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial

Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial Pubmed

Espahbodi E^{1, 3} ; Sanatkar M^{2, 3} ; Sadrossadat H³ ; Darabi Vafsi ME¹ ; Azarshahin M¹ ; Shoroughi M³

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1. Department of Anesthesiology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Anesthesiology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Anesthesiology, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Acta Medica Iranica Published:2015

Abstract

Profound bradycardia during eye surgery is a potentially serious event. In clinical practice oculo-cardiac reflex (OCR) is most often encountered during squint surgery. The objective of this study was to assess the occurrence of OCR and prove the effect of ketamine as an induction drug and anticholinergic premedication (atropine) to prevent OCR. This study comprised 90 patients (aged 4-10 years) operated for squint surgery under general anesthesia. Patients were divided into three groups. Using block randomization, each patient enrolled in one of the three groups based on organized random table prepared by statistician. Group K received ketamine as an induction drug, Group A was premedicated with intravenous injection of atropine and Group C did not receive any premedication. Patients were monitored during operation for any bradycardia or dysrhythmias. The observed data showed occurrence of 63% OCR in Group C as compared to 43% in group A and only 20% in Group K. Current study showed that induction with ketamine in the patients of squint surgery under general anesthesia definitely obtunds OCR and prevents any untoward effects of dysrhythmias during eye surgery. © 2015 Tehran University of Medical Sciences. All rights reserved.

Style	Citing Format
MLA	Espahbodi E, et al.. "Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial." Acta Medica Iranica, vol. 53, no. 3, 2015, pp. 158-161.
APA	Espahbodi E, Sanatkar M, Sadrossadat H, Darabi Vafsi ME, Azarshahin M, Shoroughi M (2015). Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial. Acta Medica Iranica, 53(3), 158-161.
Chicago	Espahbodi E, Sanatkar M, Sadrossadat H, Darabi Vafsi ME, Azarshahin M, Shoroughi M. "Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial." Acta Medica Iranica 53, no. 3 (2015): 158-161.
Harvard	Espahbodi E et al. (2015) 'Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial', Acta Medica Iranica, 53(3), pp. 158-161.
Vancouver	Espahbodi E, Sanatkar M, Sadrossadat H, Darabi Vafsi ME, Azarshahin M, Shoroughi M. Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial. Acta Medica Iranica. 2015;53(3):158-161.
BibTex	@article{ author = {Espahbodi E and Sanatkar M and Sadrossadat H and Darabi Vafsi ME and Azarshahin M and Shoroughi M}, title = {Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial}, journal = {Acta Medica Iranica}, volume = {53}, number = {3}, pages = {158-161}, year = {2015} }
RIS	TY - JOUR AU - Espahbodi E AU - Sanatkar M AU - Sadrossadat H AU - Darabi Vafsi ME AU - Azarshahin M AU - Shoroughi M TI - Ketamine or Atropine: Which One Better Prevents Oculocardiac Reflex During Eye Surgery? a Prospective Randomized Clinical Trial JO - Acta Medica Iranica VL - 53 IS - 3 SP - 158 EP - 161 PY - 2015 ER -

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