Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behcet’S Disease Publisher Pubmed



Bazvand F¹ ; Zarei M¹ ; Ebrahimiadib N² ; Karkhaneh R¹ ; Davoudi S² ; Soleimanzadeh M¹ ; Sharifian E¹ ; Roohipoor R¹ ; Modjtahedi BS² Show Affiliations
Source: Seminars in Ophthalmology Published:2017

Abstract

Purpose: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behcet’s disease as well as the relationship between visual acuity and angiographic findings. Methods: Retrospective chart review of patients with Behcet’s disease seen at the Farabi Eye Hospital. Results: Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively. Panuveitis was the most frequent type of uveitis (76%). Among patients with FA, vasculitis was the most common finding (87%) and it was significantly more severe among patients with visual acuity less than 20/200. Macular leakage (P = 0.001), arterial narrowing (P = 0.000), and posterior retinal vasculitis (P = 0.002) on FA were all associated with worsening final visual acuity. Conclusion: The most common ocular findings in Behcet’s disease were panuveitis and vasculitis. Location of vasculitis, arterial narrowing, and macular leakage on initial FA may predict visual prognosis. © Taylor & Francis.