Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis

Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis

Nasab SDM^{1, 2} ; Zali F³ ; Kaghazian H^{1, 2} ; Aghasadeghi MR^{1, 4} ; Mardani R⁵ ; Gachkar L⁶ ; Vasmehjani AA⁷ ; Ahmadi N⁸ ; Ghasemzadeh A⁹

Show Affiliations

1. Department of Research and Development, Production and Research Complex, Pasteur Institute of Iran, Iran
2. Viral vaccine research center, Pasteur Institute of Iran, Iran
3. Department of Clinical Biochemistry, Faculty of Medicine, Tehran University of Medical Science, Tehran, Iran
4. Department of Hepatitis, AIDS and Blood-borne diseases, Pasteur Institute of Iran, Tehran, Iran
5. Department of Viral vaccines, Pasteur Institute of Iran, Tehran, Iran
6. Infectious Diseases and Tropical Medicine Research Center, Infectious Diseases Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
7. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
8. Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
9. Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Gastroenterology and Hepatology from Bed to Bench Published:2020

Abstract

Aim: This study aimed to determine the prevalence of Human Astroviruses (HAstVs), enteric Adenoviruses (HAdVs), and Sapoviruses (SaVs) in acute diarrhea patients, as well as their relation to age, sex, and season. Background: Acute gastroenteritis is one of the most common diseases affecting children <5 years old and viral agents with approximately >75% are the major causative agent of acute infectious diarrhea. After Rotavirus and Norovirus, the greater viral agents of acute gastroenteritis include HAstVs, HAdVs, and SaVs. To the best of our knowledge, there are sparse studies in Iran detecting at least three enteric viruses as causative agents of diarrhea simultaneously. Methods: The sample was collected from children referring to pediatric medical centers in Tehran, Iran; they were tested for Astrovirus, enteric Adenovirus, and Sapovirus by conventional PCR method. The association of incidence of viral enteric agents was evaluated with age, sex and seasonal pattern in children <5 years old. Results: The positive case number among acute gastroenteritis patients was 17/120 (14.1%). Patients ranged in age within 1-60 months, but 52.9% were aged ≤ 12 months. Males comprised the majority (70.6), and the male: female ratio was 2.4. HAstV was the most frequently detected virus (6.7%), while SaVs were detected only in 2.5% of cases. Mixed infections were not detected in these samples. The highest rate of HAstV was identified in winter (66.7%), HAdV in fall (66.7%), and SaV in winter (33.3%). Conclusion: These findings underscore the importance of monitoring the epidemiology of HAstV, HAdV, and SaV as causative agents of viral diarrhea infections. © 2020 RIGLD, Research Institute for Gastroenterology and Liver Diseases

2. Molecular Characterization of Human Astrovirus Infection in Children Under 5 Years of Age With Acute Gastroenteritis in Tehran, Iran, 2021–2022: Co-Infection With Rotavirus, Virus Genes (2024)

3. Molecular Analysis of Human Adenoviruses in Hospitalized Children <5 Years Old With Acute Gastroenteritis in Tehran, Iran, Journal of Medical Virology (2019)

Experts (# of related papers)

Somayeh Jalilvand (2)

Sayed Mahdi Marashi (1)

Style	Citing Format
MLA	Nasab SDM, et al.. "Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis." Gastroenterology and Hepatology from Bed to Bench, vol. 13, no. , 2020, pp. S122-S127.
APA	Nasab SDM, Zali F, Kaghazian H, Aghasadeghi MR, Mardani R, Gachkar L, Vasmehjani AA, Ahmadi N, Ghasemzadeh A (2020). Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis. Gastroenterology and Hepatology from Bed to Bench, 13(), S122-S127.
Chicago	Nasab SDM, Zali F, Kaghazian H, Aghasadeghi MR, Mardani R, Gachkar L, Vasmehjani AA, Ahmadi N, Ghasemzadeh A. "Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis." Gastroenterology and Hepatology from Bed to Bench 13, no. (2020): S122-S127.
Harvard	Nasab SDM et al. (2020) 'Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis', Gastroenterology and Hepatology from Bed to Bench, 13(), pp. S122-S127.
Vancouver	Nasab SDM, Zali F, Kaghazian H, Aghasadeghi MR, Mardani R, Gachkar L, et al.. Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis. Gastroenterology and Hepatology from Bed to Bench. 2020;13():S122-S127.
BibTex	@article{ author = {Nasab SDM and Zali F and Kaghazian H and Aghasadeghi MR and Mardani R and Gachkar L and Vasmehjani AA and Ahmadi N and Ghasemzadeh A}, title = {Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis}, journal = {Gastroenterology and Hepatology from Bed to Bench}, volume = {13}, number = {}, pages = {S122-S127}, year = {2020} }
RIS	TY - JOUR AU - Nasab SDM AU - Zali F AU - Kaghazian H AU - Aghasadeghi MR AU - Mardani R AU - Gachkar L AU - Vasmehjani AA AU - Ahmadi N AU - Ghasemzadeh A TI - Prevalence of Astrovirus, Adenovirus, and Sapovirus Infections Among Iranian Children With Acute Gastroenteritis JO - Gastroenterology and Hepatology from Bed to Bench VL - 13 IS - SP - S122 EP - S127 PY - 2020 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract