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Evaluation and Relation of Oral Health-Related Quality of Life and Oral Health Status in Thalassemia Major Patients, a Cross-Sectional Study Publisher Pubmed



Abbasi F1 ; Tabesh A1 ; Yavari A2 ; Makaremi R2 ; Bizhani O2 ; Mahmood M2, 3
Authors
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Authors Affiliations
  1. 1. Dental Research Center, Department of Oral Medicine, Dental research institute, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Student Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Restorative Dentistry, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Source: BMC Oral Health Published:2023


Abstract

Background: Beta-Thalassemia is the most common human inherited disease, directly impacting patients’ physical and psychosocial aspects. The present study evaluated oral health status, oral health-related quality of life (OHRQoL), and their correlation in Thalassemia Major patients. Methods: Two hundred Thalassemia Major patients aged 12–49 participated in this cross-sectional study. Subjects were selected among the patients referred to the Faculty of Dentistry of Isfahan University of Medical Sciences using simple sampling. Oral Health Impact Profile 14 (OHIP 14) was used to assess OHRQoL. The decayed, Missing, and Filled Teeth (DMFT) index was used as an oral health index. SPSS 22 was used for analysis, using T and Pearson Correlation tests. Results: 53% of participants were female, and 47% were male. The mean OHIP-14 score (± SD) was 13.20 (± 7.01). The mean DMFT score was 9.54 (± 5.72). DMFT and total OHIP 14 scores correlated significantly (p < 0.001, r = 0.78). All domains of the OHIP-14 score were also significantly correlated with DMFT (p < 0.05). Conclusions: Poor oral health conditions might adversely affect OHRQoL in TM patients. It seems necessary to provide oral treatment needs in order to improve OHRQoL in patients suffering from this particular disease. © 2023, The Author(s).