In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]

In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена] Publisher Pubmed

Pourhajibagher M¹ ; Ghorbanzadeh R² ; Salehivaziri A² ; Bahador A^{3, 4}

Show Affiliations

1. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Orthodontics, Shahed University, Tehran, Iran
3. Oral Microbiology Laboratory, Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Clinical Laboratory Sciences, Bio Health Lab, Tehran, Iran

Source: Folia Medica Published:2022

Abstract

Introduction: Formation of white spots and initial carious lesions are the most important complications of fixed orthodontic treatment. Preparation of orthodontic adhesives containing antimicrobial agents might be a practical solution for the prevention of the mentioned defects. Aim: The current study aims to assess the antimicrobial and cytotoxicity effects of a conventional orthodontic adhesive containing different concentrations of nano-graphene oxide (N-GO). Materials and methods: 50 Transbond XT orthodontic adhesive discs containing 0, 1, 2, 5, and 10% N-GO were prepared and sterilized by 25 kGy Gamma irradiation. After determination of cytotoxicity potential of modified orthodontic adhesive on human gingival fibroblast (HGF) cells, antimicrobial effects of the modified orthodontic adhesive against Streptococcus mutans in the preformed cariogenic biofilms was investigated using eluted components from composite discs by comparing the viable counts of bacteria after 3, 7, 15, 30, and 60 days of the aging process in artificial saliva. Results: Based on the results, there was no cytotoxic effects of modified orthodontic adhesive on HGF cells (p>0.05). Transbond XT orthodontic adhesive containing 5 and 10 wt% N-GO reduced considerably the mean total viable counts of S. mutans up to 30 days (p<0.05). However, at 60 days, only 10 wt% N-GO could statistically decrease the colony-forming unit (CFU)/mL of test microorganisms. Antimicrobial activity of eluted components from modified orthodontic adhesive discs against S. mutans was in line with the concentration of N-GO. Conclusions: At 5% and 10% concentrations, a modified orthodontic adhesive containing N-GO has a significant antimicrobial activity against S. mutans in cariogenic biofilms. © Folia Medica 2022.

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Experts (# of related papers)

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Maryam Pourhajibagher (8)

Abbas Bahador (8)

Style	Citing Format
MLA	Pourhajibagher M, et al.. "In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]." Folia Medica, vol. 64, no. 1, 2022, pp. 110-116.
APA	Pourhajibagher M, Ghorbanzadeh R, Salehivaziri A, Bahador A (2022). In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]. Folia Medica, 64(1), 110-116.
Chicago	Pourhajibagher M, Ghorbanzadeh R, Salehivaziri A, Bahador A. "In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]." Folia Medica 64, no. 1 (2022): 110-116.
Harvard	Pourhajibagher M et al. (2022) 'In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]', Folia Medica, 64(1), pp. 110-116.
Vancouver	Pourhajibagher M, Ghorbanzadeh R, Salehivaziri A, Bahador A. In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]. Folia Medica. 2022;64(1):110-116.
BibTex	@article{ author = {Pourhajibagher M and Ghorbanzadeh R and Salehivaziri A and Bahador A}, title = {In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]}, journal = {Folia Medica}, volume = {64}, number = {1}, pages = {110-116}, year = {2022} }
RIS	TY - JOUR AU - Pourhajibagher M AU - Ghorbanzadeh R AU - Salehivaziri A AU - Bahador A TI - In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена] JO - Folia Medica VL - 64 IS - 1 SP - 110 EP - 116 PY - 2022 ER -

Style

Citing Format

MLA

Pourhajibagher M, et al.. "In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]." Folia Medica, vol. 64, no. 1, 2022, pp. 110-116.

APA

Pourhajibagher M, Ghorbanzadeh R, Salehivaziri A, Bahador A (2022). In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]. Folia Medica, 64(1), 110-116.

Chicago

Pourhajibagher M, Ghorbanzadeh R, Salehivaziri A, Bahador A. "In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]." Folia Medica 64, no. 1 (2022): 110-116.

Harvard

Pourhajibagher M et al. (2022) 'In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]', Folia Medica, 64(1), pp. 110-116.

Vancouver

Pourhajibagher M, Ghorbanzadeh R, Salehivaziri A, Bahador A. In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]. Folia Medica. 2022;64(1):110-116.

BibTex

@article{ author = {Pourhajibagher M and Ghorbanzadeh R and Salehivaziri A and Bahador A}, title = {In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]}, journal = {Folia Medica}, volume = {64}, number = {1}, pages = {110-116}, year = {2022} }

RIS

TY - JOUR
AU - Pourhajibagher M
AU - Ghorbanzadeh R
AU - Salehivaziri A
AU - Bahador A
TI - In Vitro Assessments of Antimicrobial Potential and Cytotoxicity Activity of an Orthodontic Adhesive Doped With Nano-Graphene Oxide; [In Vitro Оценка Антимикробного Потенциала И Цитотоксической Активности Ортодонтического Адгезива, Легированного Нанооксидом Графена]
JO - Folia Medica
VL - 64
IS - 1
SP - 110
EP - 116
PY - 2022
ER -

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