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Cardiac Fat Pat Change After Laparoscopic Sleeve Gastrectomy and Roux-En-Y Gastric Bypass Surgery: A Systematic Review and Meta-Analysis Publisher Pubmed



Sheikhbahaei E1 ; Tavassoli Naini P2 ; Agharazi M2 ; Pouramini A3 ; Rostami S4 ; Bakhshaei S5 ; Valizadeh R6 ; Heshmat Ghahdarijani K7 ; Shiravi A2 ; Shahabi S8
Authors
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Authors Affiliations
  1. 1. Isfahan Minimally Invasive Surgery and Obesity Research Center, Alzahra University Hospital, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Student Research Committee, Dnipro Medical Institute of Conventional and Traditional Medicine, Dnipro, Ukraine
  5. 5. Temecula Valley Hospital, Temecula, CA, United States
  6. 6. Department of Epidemiology and Biostatistics, School of Public Health, Urmia University of Medical Sciences, Urmia, Iran
  7. 7. Isfahan Cardiovascular Research Center, Chamran University Hospital, Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  8. 8. Department of Surgery, Minimally Invasive Surgery Research Center, Hazrat-e Rasool General Hospital, Iran University of Medical Sciences, Tehran, Iran

Source: Surgery for Obesity and Related Diseases Published:2023


Abstract

Cardiac fat pad is a metabolically active organ that plays a role in energy homeostasis and cardiovascular diseases and generates inflammatory cytokines. Many studies have shown remarkable associations between cardiac fat thickness and cardiovascular diseases, making it a valuable target for interventions. Our meta-analysis aimed to investigate the effects of the 2 most popular bariatric surgeries (sleeve gastrectomy [SG] and Roux-en-Y gastric bypass [RYGB]) in cardiac fat pad reduction. A systematic review of the literature was done by searching in Scopus, Web of Science, Cochrane, and PubMed for articles published by September 16, 2022. This review followed the meta-analysis rules based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Nineteen studies met the inclusion criteria out of 128 potentially useful studies, including a total number of 822 patients. The results of subgroup analysis on the type of surgery showed that bariatric surgeries decreased the mean fat pad diameter, but the reduction was greater in SG than in RYGB. Epicardial and pericardial fat type showed a significant decrease of fat pad diameter. The results of subgroup analysis indicated RYGB had a significant reduction in mean fat pad volume. Computed tomography scan and cardiac magnetic resonance imaging showed a significant reduction of the mean cardiac fat pad volume. Epicardial and paracardial fat type showed a significant decrease in volume. The cardiac fat pad diameter and volume were significantly reduced after bariatric surgeries. SG showed greater reduction in fat pad diameter in comparison with RYGB, and RYGB had a significant reduction in mean fat pad volume. © 2023
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