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Prevalence of Osteoporosis in the Iranian Population: A Systematic Review and Meta-Analysis Publisher



Fahimfar N1, 2 ; Hesari E1 ; Mansourzadeh MJ1 ; Khalagi K1, 3 ; Sanjari M1 ; Hajivalizadeh S1 ; Tanha K4 ; Moheimani H5 ; Hajivalizadeh F6 ; Irani AD7 ; Nematollahi S8 ; Larijani B9 ; Ostovar A1, 2, 10
Authors
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Authors Affiliations
  1. 1. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Oxford Vaccine Group, Department of Pediatrics, University of Oxford, Oxford, United Kingdom
  5. 5. Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States
  6. 6. Center for Non-Communicable Disease Control & Prevention, Deputy of Public Health, Ministry of Health and Medical Education, Tehran, Iran
  7. 7. Departments of Epidemiology and Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
  8. 8. School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada
  9. 9. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. Endocrinology and Metabolism Research Institute, No. 10, Jalal-Al-Ahmad Ave., Tehran, Iran

Source: Journal of Diabetes and Metabolic Disorders Published:2023


Abstract

Purpose: The prevalence of osteoporosis increases as the population ages. The aim of this study was to conduct a systematic review and meta-analysis to estimate the prevalence of osteoporosis among the general population ≥ 50 years old in Iran. Methods: Multiple databases including Scopus, WOS, Medline, Embase, and Persian databases (SID and Magiran) were systematically searched to identify relevant research papers. All population-based studies estimating the prevalence of osteoporosis in the Iranian population were included and imported into Endnote software. Two authors independently reviewed the articles. The Newcastle-Ottawa Scale was used to assess the risk of bias. Statistical analysis was performed using Stata software, and a significance level of 0.05 was applied to the analyses. Results: Totally 2117 documents were retrieved from the databases up until October 11, 2022. After reading the full texts, 10 documents were included in the study. Our results indicated that the pooled prevalence of osteoporosis in the femoral neck region was 0.19 (95%CI: 0.12–0.26) and 0.19 (95%CI: 0.13–0.25) for women and men, respectively. Pooled prevalence of spinal osteoporosis was 0.29 (95%CI: 0.21–0.38) among women and 0.16 (95%CI: 0.12–0.19) among men. The total pooled prevalence of osteoporosis was 0.38 (95%CI: 0.29–0.48) for women and 0.25 (95%CI: 0.22–0.29) for men. Conclusion: Our study highlights the elevated prevalence of osteoporosis among individuals aged 50 years and older, with females exhibiting higher rates. Notably, osteoporosis in the femoral neck region demonstrated the lowest prevalence in both sexes. The implementation of comprehensive strategies is imperative to address osteoporosis problems effectively. © 2023, The Author(s), under exclusive licence to Tehran University of Medical Sciences.
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