Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions

Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions Publisher

Adib M¹ ; Ghanbarlou M¹ ; Soheilizad M² ; Bahadorikhalili S³ ; Larijani B³ ; Mahdavi M³

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1. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
2. Department of Chemistry, Tarbiat Modares University, P.O. Box 14115â€�175, Tehran, Iran
3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Tetrahedron Letters Published:2021

Abstract

An efficient synthesis of 4H-chromeno[4,3-b]furo[2,3-d]pyridine-1-carboxylates as novel tetracyclic coumarin-fused furo-pyridone scaffolds is described. The protocol involves the three-component reaction of 4-chloro-coumarin-3-carbaldehyde, dimethyl acetylenedicarboxylate and isocyanides, followed by the addition of primary amines to produce the corresponding products in 78–92% yield. © 2021

Style	Citing Format
MLA	Adib M, et al.. "Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions." Tetrahedron Letters, vol. 68, no. , 2021, pp. -.
APA	Adib M, Ghanbarlou M, Soheilizad M, Bahadorikhalili S, Larijani B, Mahdavi M (2021). Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions. Tetrahedron Letters, 68(), -.
Chicago	Adib M, Ghanbarlou M, Soheilizad M, Bahadorikhalili S, Larijani B, Mahdavi M. "Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions." Tetrahedron Letters 68, no. (2021): -.
Harvard	Adib M et al. (2021) 'Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions', Tetrahedron Letters, 68(), pp. -.
Vancouver	Adib M, Ghanbarlou M, Soheilizad M, Bahadorikhalili S, Larijani B, Mahdavi M. Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions. Tetrahedron Letters. 2021;68():-.
BibTex	@article{ author = {Adib M and Ghanbarlou M and Soheilizad M and Bahadorikhalili S and Larijani B and Mahdavi M}, title = {Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions}, journal = {Tetrahedron Letters}, volume = {68}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Adib M AU - Ghanbarlou M AU - Soheilizad M AU - Bahadorikhalili S AU - Larijani B AU - Mahdavi M TI - Synthesis of Novel Tetracyclic Coumarin-Fused Furo-Pyridone Scaffolds Via Sequential N-Arylation and Intramolecular Amidation Reactions JO - Tetrahedron Letters VL - 68 IS - SP - EP - PY - 2021 ER -

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