Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate

Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate Publisher

Boojar MMA^{1, 2} ; Boojar MMA^{1, 2} ; Golmohammad S³ ; Bahrehbar I³

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1. Department of Pharmacology and Toxicology, Baqiyatallah University of Medical Sciences, Tehran, Iran
2. Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran

Source: Data in Brief Published:2018

Abstract

Ceramide pathway is a key regulator in cell proliferation and apoptosis and oxidative stress up-regulate ceramides. Acid ceramidase (ACDase), neutral sphingomyelinase (NSMase) and glucosylceramide synthase (GCS) are critical enzymatic systems in ceramide metabolism. Our data represent the comparative assessment of Hesperetin (Hst) and hesperetin-7-O-acetate (HTA) effects on A-494 renal carcinoma cells include cell survival, caspase-3 and 9 activities, total cellular ceramide and the activities of ACDase, NSMase, GCS and superoxide dismutase (SOD). Data reveals potentiating effects of both HTA and Hst on ceramide pathway and may offer a novel tool in human renal cell carcinoma therapy. © 2018 The Authors

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Ahmad Reza Dehpour (1)

Style	Citing Format
MLA	Boojar MMA, et al.. "Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate." Data in Brief, vol. 20, no. , 2018, pp. 596-601.
APA	Boojar MMA, Boojar MMA, Golmohammad S, Bahrehbar I (2018). Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate. Data in Brief, 20(), 596-601.
Chicago	Boojar MMA, Boojar MMA, Golmohammad S, Bahrehbar I. "Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate." Data in Brief 20, no. (2018): 596-601.
Harvard	Boojar MMA et al. (2018) 'Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate', Data in Brief, 20(), pp. 596-601.
Vancouver	Boojar MMA, Boojar MMA, Golmohammad S, Bahrehbar I. Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate. Data in Brief. 2018;20():596-601.
BibTex	@article{ author = {Boojar MMA and Boojar MMA and Golmohammad S and Bahrehbar I}, title = {Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate}, journal = {Data in Brief}, volume = {20}, number = {}, pages = {596-601}, year = {2018} }
RIS	TY - JOUR AU - Boojar MMA AU - Boojar MMA AU - Golmohammad S AU - Bahrehbar I TI - Data on Cell Survival, Apoptosis, Ceramide Metabolism and Oxidative Stress in A-494 Renal Cell Carcinoma Cell Line Treated With Hesperetin and Hesperetin-7-O-Acetate JO - Data in Brief VL - 20 IS - SP - 596 EP - 601 PY - 2018 ER -

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