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Mo (Co) 6 -Assisted Pd-Supported Magnetic Graphene Oxide-Catalyzed Carbonylation-Cyclization As an Efficient Way for the Synthesis of 4(3H)-Quinazolinones Publisher



Bahadorikhalili S1 ; Ansari S2 ; Hamedifar H2 ; Mamani L3 ; Babaei M1 ; Eqra R1 ; Mahdavi M4
Authors
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Authors Affiliations
  1. 1. Institute of Mechanics, Iranian Space Research Center, Shiraz, Iran
  2. 2. CinnaGen Medical Biotechnology Research Center, Alborz University of Medical Sciences, Karaj, Iran
  3. 3. Department of Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran
  4. 4. Endocrinology and Metabolism Research Centre, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Science, Tehran, Iran

Source: Applied Organometallic Chemistry Published:2019


Abstract

In this paper, a novel catalyst is introduced based on the immobilization of palladium on modified magnetic graphene oxide nanoparticles. The catalyst is characterized by several methods, including transmission electron microscopy, scanning electron microscopy, X-ray fluorescence, vibrating-sample magnetometer, Fourier transform-infrared and dynamic light scattering (DLS) analysis. The activity of the catalyst was investigated in the synthesis of 4(3H)-quinazolinones via Pd-catalyzed carbonylation-cyclization of N-(2-bromoaryl) benzimidamides by Mo (CO) 6 . The Mo (CO) 6 is used as a carbon monoxide source for performing the reaction under mild conditions. The catalyst showed good reusability, and no change in activity was observed after 10 cycles of recovery. © 2019 John Wiley & Sons, Ltd.