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Systemic Inflammatory Response Index in Iga Nephropathy; a Review to Recent Findings Publisher



Mojtahedi S Y ; Ashournia P ; Pourpashang P
Authors

Source: Journal of Preventive Epidemiology Published:2026


Abstract

Numerous studies have shown that patients with IgA nephropathy (IgAN) exhibit a range of systemic inflammatory indicators that correlate with clinical outcomes. Elevated neutrophil-to-lymphocyte ratios and systemic immune inflammation index scores have been associated with poorer renal survival and strengthened risk of progression to end-stage renal disease (ESRD). The relationship between systemic inflammation and IgAN progression provides valuable insights into potential therapeutic strategies and prognostic implications for cases suffering from this disease. However, this tool has some limitations which should be respected following its application. © 2026 The Author(s);.