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Efficient Three-Step Synthesis of Benzo[E]Imidazo[1,2-C][1,2,3]Triazines Publisher



Pilali H1 ; Kamazani SF2 ; Moradi S1 ; Moghimi S2 ; Mahdavi M2 ; Firoozpour L3 ; Shafiee A2 ; Foroumadi A2, 3
Authors
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Authors Affiliations
  1. 1. Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran
  2. 2. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Synthetic Communications Published:2016


Abstract

A novel three-step sequence toward benzo[e]imidazo[1,2-c][1,2,3]triazine derivatives is investigated. This pathway started from commercially available starting materials afforded 5a-h in good to excellent yields. In this method, we took the advantage of diazonium chemistry, which was followed by intramolecular N-N bond formation in the construction of N-rich cycles. © 2016 Taylor & Francis.