Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent

Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent

Tehrani MB¹ ; Jalaeian B¹ ; Shamsa H¹ ; Souri E¹

Show Affiliations

1. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Research Journal of Pharmaceutical# Biological and Chemical Sciences Published:2016

Abstract

A simple, sensitive and accurate spectrophotometric method for the determination of Co(II) using newly synthesized reagent, 2-(naphthalen-2-yl)-2-oxoacetaldehyde oxime, has been developed. The reagent, 2-(naphthalen-2-yl)-2-oxoacetaldehyde oxime (2NGA), was synthesized based on the reaction of 2-acethyl naphthalene with amyl nitrite in sodium methoxide and reflux at 40°C for 50h. 2NGA reacts with Co2+ to form stable yellow complex in basic media which is easily extractable with chloroform. Beer's law was obeyed over the concentration range of 1-15 μg/ml with r2 = 0.9990 and RSD of slope 0.822. Within-day and between-day precision and accuracy values were less than 2.6%. Finally, the method has been applied to a vit B12 product successfully and the results compared with atomic absorption method. The results showed that there was no significant difference between two methods.

Style	Citing Format
MLA	Tehrani MB, et al.. "Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent." Research Journal of Pharmaceutical# Biological and Chemical Sciences, vol. 7, no. 6, 2016, pp. 1374-1380.
APA	Tehrani MB, Jalaeian B, Shamsa H, Souri E (2016). Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent. Research Journal of Pharmaceutical# Biological and Chemical Sciences, 7(6), 1374-1380.
Chicago	Tehrani MB, Jalaeian B, Shamsa H, Souri E. "Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent." Research Journal of Pharmaceutical# Biological and Chemical Sciences 7, no. 6 (2016): 1374-1380.
Harvard	Tehrani MB et al. (2016) 'Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent', Research Journal of Pharmaceutical# Biological and Chemical Sciences, 7(6), pp. 1374-1380.
Vancouver	Tehrani MB, Jalaeian B, Shamsa H, Souri E. Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent. Research Journal of Pharmaceutical# Biological and Chemical Sciences. 2016;7(6):1374-1380.
BibTex	@article{ author = {Tehrani MB and Jalaeian B and Shamsa H and Souri E}, title = {Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent}, journal = {Research Journal of Pharmaceutical# Biological and Chemical Sciences}, volume = {7}, number = {6}, pages = {1374-1380}, year = {2016} }
RIS	TY - JOUR AU - Tehrani MB AU - Jalaeian B AU - Shamsa H AU - Souri E TI - Spectrophotometric Determination of Trace Co (Ii) With Naphthylglyoxalaldoxime As a Newly Synthesized Reagent JO - Research Journal of Pharmaceutical# Biological and Chemical Sciences VL - 7 IS - 6 SP - 1374 EP - 1380 PY - 2016 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract