Study of Steroid Effects on Graft and Inner Ear Outcomes in Tympanoplasty: Randomized Controlled Trial Publisher Pubmed



Kouhi A¹ ; Dabiri S¹ ; Amali A¹ ; Yazdani N¹ ; Baroodabi M¹ ; Kouchakinejad T¹ ; Mohseni A¹ Show Affiliations
Source: Ear# Nose and Throat Journal Published:2018

Abstract

More studies are needed to investigate the side effects of steroids in tympanoplasty, owing to the paucity of such studies in the literature. This randomized, controlled clinical trial included 59 patients with chronic otitis media who underwent tympanoplasty and were randomized after surgery to a systemic steroid or no steroid treatment. Patients were randomized into two groups. Perforation size, graft outcome, and complications such as tinnitus and hearing loss were compared between the two groups. Postsurgical steroid injection had no effect on graft outcome (p = 0.927) or tinnitus (p = 0.478). Tympanic membrane perforation (p = 0.92), plaque size (p = 0.94), bleeding amount (p = 0.38), and mucosal status (p = 0.96) during surgery had no effect on graft outcome after the tympanoplasty. In conclusion, administration of steroids after tympanoplasty failed to improve outcome and may put the patient at risk of side effects. © 2018 Vendome Group, LLC.