Effectiveness of Mindfulness-Based Cognitive Therapy for Individuals With Premenstrual Syndrome: A Systematic Review and Meta-Analysis Publisher



Nasrollahimola N ; Shaliha F ; Griffiths M D ; Alimoradi Z
Source: Journal of Behavioral and Cognitive Therapy Published:2027

Abstract

Background: Premenstrual syndrome (PMS) is a common condition affecting women of reproductive age, characterized by a variety of physical, emotional, and behavioral symptoms that can significantly disrupt daily life and overall well-being. Given the limitations of traditional pharmacological treatments, there is a growing interest in exploring non-pharmacological interventions. Objective: The present systematic review and meta-analysis aimed to assess the effectiveness of mindfulness-based cognitive therapy (MBCT) in reducing PMS symptoms and enhancing psychological health. Methods: The review was conducted following PRISMA guidelines. A comprehensive literature search was performed across eight academic databases to identify studies evaluating the impact of MBCT on PMS-related outcomes. The eligibility criteria were developed based on the PICOS framework, focusing on women diagnosed with PMS who underwent MBCT. Of the 1,213 papers initially identified, five randomized controlled trials and one before-after feasibility study met the inclusion criteria, involving a total of 384 participants. Meta-analyses were performed using a random-effects model, and effect sizes were reported as standardized mean differences (SMD) with 95% confidence intervals (CIs). Results: Meta-analysis of three randomized controlled trials showed a significant reduction in PMS symptoms (SMD = -1.74, 95% CI: −2.13 to −1.35; I2 = 0%). Meta-analysis of two randomized controlled trials showed significant improvement in health-related quality of life (SMD = 0.89, 95% CI: 0.51 to 1.27; I2 = 29.96%). Narrative synthesis of secondary outcomes (depression, anxiety, health-promoting behaviors, work-related quality of life, PMS impact in daily life, and mindfulness) also suggested potential benefits of MBCT. Conclusion: Preliminary evidence suggests that MBCT may alleviate PMS symptoms and improve psychological well-being. However, the limited number of studies, methodological limitations (particularly lack of blinding and inadequate randomization procedures), and restricted geographical representation (five of the six studies were conducted in Iran) warrant cautious interpretation. Larger, methodologically rigorous, and geographically diverse randomized controlled trials with longer follow-up are needed to confirm these findings. © 2026 Association Francaise de Therapie Comportementale et Cognitive