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Health Risk Assessment and Determination of Bisphenol a and Aflatoxin M1 in Infant Formula Publisher



Mirzaei G1 ; Yazdanfar N2 ; Shariatifar N1 ; Molaee Aghaee E1 ; Sadighara P1
Authors
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Authors Affiliations
  1. 1. Department of Environmental Health Engineering, Division of Food Safety and Hygiene, School of public health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Iranian Research and Development Center for Chemical Industries, ACECR, Tehran, Iran

Source: BMC Nutrition Published:2025


Abstract

Background: Bisphenol A (BPA) is one of the chemical compounds used in food packaging, so it can migrate from the packaging into food. Also, environmental pollution of this compound is high due to its high use. Therefore, it may enter food chains through the environment. Aflatoxin M1 (AFM1) is one of the common mycotoxins in milk. Its presence has been reported worldwide. Infant formula is an alternative to human milk. The main ingredient of this product is cow’s milk. Aims: This study aimed to investigate the levels and risk assessment of BPA and aflatoxin M1 in infant formula. Methods: Samples were purchased from 7 leading brands of infant formula in pharmacies. The samples were extracted according to common protocols and then injected into HPLC and analyzed with a fluorescence detector for both contaminants. Results: BPA wasn’t detected in infant formula samples, but the presence of AFM1was confirmed in 11% of the samples. Of course, there is no risk in this regard with the risk assessment. Conclusion: Infant formula samples are not of concern for infants in terms of BPA and aflatoxin M1. However, continuous monitoring is recommended for this product. © The Author(s) 2025.
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