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A Novel and Reusable Magnetic Nanocatalyst Developed Based on Graphene Oxide Incorporated Strontium Nanoparticles for the Facial Synthesis of Β-Enamino Ketones Under Solvent-Free Conditions Publisher



Mousavi SR1 ; Sereshti H2 ; Rashidi Nodeh H2, 3 ; Foroumadi A1, 4
Authors
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Authors Affiliations
  1. 1. Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Chemistry, Faculty of Science, University of Tehran, Tehran, Iran
  3. 3. Department of Food Science & Technology, Faculty of Food Industry and Agriculture, Standard Research Institute (SRI), Karaj P.O. Box: 31745-139, Iran
  4. 4. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Source: Applied Organometallic Chemistry Published:2019


Abstract

A novel magnetic SrFeGO nanocatalyst (NC) was synthesized through a simple sol–gel technique by introducing strontium and iron oxide nanoparticles onto graphene. The synthesized NC was characterized using FT-IR and FE-SEM. Subsequently, the catalytic activity of SrFeGO was tested in a reaction between β-dicarbonyl compounds and aniline derivatives to gain β-enamino ketone derivatives under solvent-free conditions. It was found that SrFeGO NC is a potential catalyst for the synthesis of β-enamino ketones. The β-enamino ketone produced by such reactions could be isolated in high purity without the need for chromatographic purifications. The newly prepared magnetic graphene oxide nanocomposite could be recovered and reused for numerous times with no significant decrease in efficiency. Moreover, the protocol has the advantages of excellent yielding (up to 98%) in short a reaction time, benefitting an easy workup procedure and being environmentally friendly. © 2018 John Wiley & Sons, Ltd.