Rehacom Cognitive Rehabilitation on the Neurocognitive Status of Patients With Temporal Lobe Epilepsy After Anterior Temporal Lobectomy Publisher



Amani K ; Farahmand B ; Faghihjouibari MF ; Shafiee S ; Azizan Z ; Amini B ; Aghamollaii V ; Tafakhori A
Source: Clinical Neuropsychiatry Published:2025

Abstract

Objective: This study aims to evaluate the effectiveness of RehaCom cognitive rehabilitation in improving neurocognitive functions in patients with temporal lobe epilepsy (TLE) following anterior temporal lobectomy (ATL), a common surgical intervention for medically refractory epilepsy. Method: A total of 12 patients who had undergone ATL participated in a 10-session RehaCom rehabilitation program. Cognitive assessments were conducted pre-and post-intervention, measuring verbal memory, figural memory, attention, and executive function. Cognitive improvements were analyzed using repeated measures ANOVA and non-parametric tests to evaluate changes in performance and the effect of the surgery side on outcomes. Results: Significant improvements were observed in verbal memory, working memory, and learning ability, especially in patients who underwent left anterior temporal lobectomy. Overall, cognitive improvements were evident across both groups, though specific patterns of recovery differed depending on the side of the surgery. Conclusions: RehaCom cognitive rehabilitation significantly improves cognitive functions, particularly in memory, attention, and executive function, following ATL. The side of surgery plays a role in determining specific outcomes, with left ATL patients benefiting more in verbal memory. These findings support the use of RehaCom as a multi-domain, adaptive rehabilitation tool for enhancing cognitive recovery in TLE patients post-ATL. © 2025 Elsevier B.V., All rights reserved.