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Sclerostin in Hemodialysis Patients



Baradaran A1
Authors
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Authors Affiliations
  1. 1. Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Parathyroid Disease Published:2020

Abstract

Implication for health policy/practice/research/medical education Sclerostin is a glycoprotein with 190-amino-acid, which is mainly released by osteocytes. Sclerostin reduces bone construction following preventing the final differentiation of osteoblasts and accelerating their apoptosis. The exact role of sclerostin in dialysis patients requires further studies since some authors believe that this biomarker has a relationship with bone-vascular axis and accordingly with parathyroid function. It is possible that, sclerostin related to the all-cause mortality, coronary artery calcifications and the prevalence of heart and vascular events. © 2020 The Author(s); Published by Nickan Research Institute.
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1. The Relationship Between Plasma Sclerostin Level to Various Nutritional Factors in Hemodialysis Diabetic and Non-Diabetic Patients, Journal of Parathyroid Disease (2020)
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