Rit2 Polymorphisms: Is There a Differential Association?

Rit2 Polymorphisms: Is There a Differential Association? Publisher Pubmed

Emamalizadeh B¹ ; Jamshidi J² ; Movafagh A¹ ; Ohadi M³ ; Khaniani MS^{4, 5} ; Kazeminasab S⁶ ; Biglarian A⁷ ; Taghavi S¹ ; Motallebi M¹ ; Fazeli A¹ ; Ahmadifard A¹ ; Shahidi GA⁸ ; Petramfar P⁹ ; Shahmohammadibeni N¹⁰ Show All Authors

Emamalizadeh B¹
Jamshidi J²
Movafagh A¹
Ohadi M³
Khaniani MS^{4, 5}
Kazeminasab S⁶
Biglarian A⁷
Taghavi S¹
Motallebi M¹
Fazeli A¹
Ahmadifard A¹
Shahidi GA⁸
Petramfar P⁹
Shahmohammadibeni N¹⁰
Dadkhah T¹⁰
Khademi E¹⁰
Tafakhori A¹¹
Khaligh A¹²
Safaralizadeh T¹
Kowsari A¹³
Mirabzadeh A¹⁴
Zarneh AES¹
Khorrami M¹⁵
Shokraeian P¹⁶
Banavandi MJS¹⁷
Lima BS¹⁸
Andarva M¹
Alehabib E¹
Atakhorrami M¹
Darvish H¹

Source: Molecular Neurobiology Published:2017

Abstract

Neurological disorders include a wide variety of mostly multifactorial diseases related to the development, survival, and function of the neuron cells. Single-nucleotide polymorphisms (SNPs) have been extensively studied in neurological disorders, and in a number of instances have been reproducibly linked to disease as risk factors. The RIT2 gene has been recently shown to be associated with a number of neurological disorders, such as Parkinson’s disease (PD) and autism. In the study reported here, we investigated the association of the rs12456492 and rs16976358 SNPs of the RIT2 gene with PD, essential tremor (ET), autism, schizophrenia (SCZ), and bipolar disorder (BPD; total of 2290 patients), and 1000 controls, by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Significant association was observed between rs12456492 and two disorders, PD and ET, whereas rs16976358 was found to be associated with autism, SCZ, and BPD. Our findings are indicative of differential association between the RIT2 SNPs and different neurological disorders. © 2016, Springer Science+Business Media New York.

Related Docs

View other Related Docs

1. Vitamin D Receptor Gene Variants in Parkinson's Disease Patients, Egyptian Journal of Medical Human Genetics (2017)

2. Homozygous Mapt R406w Mutation Causing Ftdp Phenotype: A Unique Instance of a Unique Mutation, Gene (2015)

3. Common Snca Genetic Variants and Parkinson’S Disease Risk: A Systematic Review and Meta-Analysis, International Journal of Molecular Sciences (2025)

Experts (# of related papers)

View all Related Experts

Mohammad Amin Tabatabaiefar (2)

Majid Kheirollahi (2)

Style	Citing Format
MLA	Emamalizadeh B, et al.. "Rit2 Polymorphisms: Is There a Differential Association?." Molecular Neurobiology, vol. 54, no. 3, 2017, pp. 2234-2240.
APA	Emamalizadeh B, Jamshidi J, Movafagh A, Ohadi M, Khaniani MS, Kazeminasab S, Biglarian A, Taghavi S, Motallebi M, Fazeli A, Ahmadifard A, Shahidi GA, Petramfar P, Shahmohammadibeni N, Dadkhah T, Khademi E, Tafakhori A, Khaligh A, Safaralizadeh T, ... Darvish H (2017). Rit2 Polymorphisms: Is There a Differential Association?. Molecular Neurobiology, 54(3), 2234-2240.
Chicago	Emamalizadeh B, Jamshidi J, Movafagh A, Ohadi M, Khaniani MS, Kazeminasab S, Biglarian A, et al.. "Rit2 Polymorphisms: Is There a Differential Association?." Molecular Neurobiology 54, no. 3 (2017): 2234-2240.
Harvard	Emamalizadeh B et al. (2017) 'Rit2 Polymorphisms: Is There a Differential Association?', Molecular Neurobiology, 54(3), pp. 2234-2240.
Vancouver	Emamalizadeh B, Jamshidi J, Movafagh A, Ohadi M, Khaniani MS, Kazeminasab S, et al.. Rit2 Polymorphisms: Is There a Differential Association?. Molecular Neurobiology. 2017;54(3):2234-2240.
BibTex	@article{ author = {Emamalizadeh B and Jamshidi J and Movafagh A and Ohadi M and Khaniani MS and Kazeminasab S and Biglarian A and Taghavi S and Motallebi M and Fazeli A and Ahmadifard A and Shahidi GA and Petramfar P and Shahmohammadibeni N and Dadkhah T and Khademi E and Tafakhori A and Khaligh A and Safaralizadeh T and Kowsari A and Mirabzadeh A and Zarneh AES and Khorrami M and Shokraeian P and Banavandi MJS and Lima BS and Andarva M and Alehabib E and Atakhorrami M and Darvish H}, title = {Rit2 Polymorphisms: Is There a Differential Association?}, journal = {Molecular Neurobiology}, volume = {54}, number = {3}, pages = {2234-2240}, year = {2017} }
RIS	TY - JOUR AU - Emamalizadeh B AU - Jamshidi J AU - Movafagh A AU - Ohadi M AU - Khaniani MS AU - Kazeminasab S AU - Biglarian A AU - Taghavi S AU - Motallebi M AU - Fazeli A AU - Ahmadifard A AU - Shahidi GA AU - Petramfar P AU - Shahmohammadibeni N AU - Dadkhah T AU - Khademi E AU - Tafakhori A AU - Khaligh A AU - Safaralizadeh T AU - Kowsari A AU - Mirabzadeh A AU - Zarneh AES AU - Khorrami M AU - Shokraeian P AU - Banavandi MJS AU - Lima BS AU - Andarva M AU - Alehabib E AU - Atakhorrami M AU - Darvish H TI - Rit2 Polymorphisms: Is There a Differential Association? JO - Molecular Neurobiology VL - 54 IS - 3 SP - 2234 EP - 2240 PY - 2017 ER -

Style

Citing Format

MLA

Emamalizadeh B, et al.. "Rit2 Polymorphisms: Is There a Differential Association?." Molecular Neurobiology, vol. 54, no. 3, 2017, pp. 2234-2240.

APA

Emamalizadeh B, Jamshidi J, Movafagh A, Ohadi M, Khaniani MS, Kazeminasab S, Biglarian A, Taghavi S, Motallebi M, Fazeli A, Ahmadifard A, Shahidi GA, Petramfar P, Shahmohammadibeni N, Dadkhah T, Khademi E, Tafakhori A, Khaligh A, Safaralizadeh T, ... Darvish H (2017). Rit2 Polymorphisms: Is There a Differential Association?. Molecular Neurobiology, 54(3), 2234-2240.

Chicago

Emamalizadeh B, Jamshidi J, Movafagh A, Ohadi M, Khaniani MS, Kazeminasab S, Biglarian A, et al.. "Rit2 Polymorphisms: Is There a Differential Association?." Molecular Neurobiology 54, no. 3 (2017): 2234-2240.

Harvard

Emamalizadeh B et al. (2017) 'Rit2 Polymorphisms: Is There a Differential Association?', Molecular Neurobiology, 54(3), pp. 2234-2240.

Vancouver

Emamalizadeh B, Jamshidi J, Movafagh A, Ohadi M, Khaniani MS, Kazeminasab S, et al.. Rit2 Polymorphisms: Is There a Differential Association?. Molecular Neurobiology. 2017;54(3):2234-2240.

BibTex

@article{ author = {Emamalizadeh B and Jamshidi J and Movafagh A and Ohadi M and Khaniani MS and Kazeminasab S and Biglarian A and Taghavi S and Motallebi M and Fazeli A and Ahmadifard A and Shahidi GA and Petramfar P and Shahmohammadibeni N and Dadkhah T and Khademi E and Tafakhori A and Khaligh A and Safaralizadeh T and Kowsari A and Mirabzadeh A and Zarneh AES and Khorrami M and Shokraeian P and Banavandi MJS and Lima BS and Andarva M and Alehabib E and Atakhorrami M and Darvish H}, title = {Rit2 Polymorphisms: Is There a Differential Association?}, journal = {Molecular Neurobiology}, volume = {54}, number = {3}, pages = {2234-2240}, year = {2017} }

RIS

TY - JOUR
AU - Emamalizadeh B
AU - Jamshidi J
AU - Movafagh A
AU - Ohadi M
AU - Khaniani MS
AU - Kazeminasab S
AU - Biglarian A
AU - Taghavi S
AU - Motallebi M
AU - Fazeli A
AU - Ahmadifard A
AU - Shahidi GA
AU - Petramfar P
AU - Shahmohammadibeni N
AU - Dadkhah T
AU - Khademi E
AU - Tafakhori A
AU - Khaligh A
AU - Safaralizadeh T
AU - Kowsari A
AU - Mirabzadeh A
AU - Zarneh AES
AU - Khorrami M
AU - Shokraeian P
AU - Banavandi MJS
AU - Lima BS
AU - Andarva M
AU - Alehabib E
AU - Atakhorrami M
AU - Darvish H
TI - Rit2 Polymorphisms: Is There a Differential Association?
JO - Molecular Neurobiology
VL - 54
IS - 3
SP - 2234
EP - 2240
PY - 2017
ER -

Science Communicator Platform

Authors

Abstract