Developmental Disorders of the Cerebellum and Neurotrophic Factors

Developmental Disorders of the Cerebellum and Neurotrophic Factors Publisher

Pirmoradi L¹ ; Owji AA² ; Shojaei S^{3, 4}

Show Affiliations

1. Department of Physiology and Pharmacology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
2. Research Center for Psychiatry and Behavioral Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
3. Department of Human Anatomy and Cell Sciences, Faculty of Health Science, College of Medicine, University of Manitoba, Winnipeg, Canada
4. Department of Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Contemporary Clinical Neuroscience Published:2017

Abstract

The cerebellum plays a main role in motor control and also in cognition features such as attention. Thus, a disturbance in cerebellar development results in neurological disorders such as attention deficit hyperactivity disorder (ADHD), congenital ataxia, and autism. Because neurotrophic factors have established effects on the growth, proliferation, differentiation, and arborization of neurons, their role in the neurodevelopmental disorders has been investigated for decades. Results of numerous studies have shown changes in serum or tissue neurotrophic factor levels, as well as alterations in their receptors and components of their signaling pathways in these types of the neurodevelopmental diseases. In this chapter, we provide a brief overview of neurotrophic factors and their role in cerebellar development and then focus on the roles of the neurotrophin system in developmental disorders and diseases of the cerebellum. © 2017, Springer International Publishing AG.

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Style	Citing Format
MLA	Pirmoradi L, Owji AA, Shojaei S. "Developmental Disorders of the Cerebellum and Neurotrophic Factors." Contemporary Clinical Neuroscience, vol. , no. , 2017, pp. 129-151.
APA	Pirmoradi L, Owji AA, Shojaei S (2017). Developmental Disorders of the Cerebellum and Neurotrophic Factors. Contemporary Clinical Neuroscience, (), 129-151.
Chicago	Pirmoradi L, Owji AA, Shojaei S. "Developmental Disorders of the Cerebellum and Neurotrophic Factors." Contemporary Clinical Neuroscience , no. (2017): 129-151.
Harvard	Pirmoradi L, Owji AA, Shojaei S (2017) 'Developmental Disorders of the Cerebellum and Neurotrophic Factors', Contemporary Clinical Neuroscience, (), pp. 129-151.
Vancouver	Pirmoradi L, Owji AA, Shojaei S. Developmental Disorders of the Cerebellum and Neurotrophic Factors. Contemporary Clinical Neuroscience. 2017;():129-151.
BibTex	@article{ author = {Pirmoradi L and Owji AA and Shojaei S}, title = {Developmental Disorders of the Cerebellum and Neurotrophic Factors}, journal = {Contemporary Clinical Neuroscience}, volume = {}, number = {}, pages = {129-151}, year = {2017} }
RIS	TY - JOUR AU - Pirmoradi L AU - Owji AA AU - Shojaei S TI - Developmental Disorders of the Cerebellum and Neurotrophic Factors JO - Contemporary Clinical Neuroscience VL - IS - SP - 129 EP - 151 PY - 2017 ER -

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