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Lexical Retrieval or Semantic Knowledge? Which One Causes Naming Errors in Patients With Mild and Moderate Alzheimer's Disease? Publisher



Salehi M1 ; Reisi M2 ; Ghasisin L3
Authors
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Authors Affiliations
  1. 1. Studes Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Neurology, Amin Hospital, Isfahan, Iran
  3. 3. Communication Disorders Research Center, Isfahan University of Medical Sciences, Department of Speech Therapy, Faculty of Rehabilitation, Hezar Jerib Street, Isfahan, 81745-164, Iran

Source: Dementia and Geriatric Cognitive Disorders Extra Published:2017


Abstract

Background: The purpose of the study was to analyze naming errors in patients with Alz-heimer's disease in comparison to healthy subjects and determine the underlying cause of naming errors in these patients. Method: In this study, we included 35 healthy elderly subjects, 23 patients with mild Alzheimer's disease, and 23 with moderate Alzheimer's disease. Forty-five images were used to determine the type of naming errors, and to identify the underlying cause of errors, matching an image with a written word was used. Results: Patients with Alz-heimer's disease had more naming errors compared with the group of healthy elderly, and patients with moderate Alzheimer's disease showed a slower reaction in matching an image with a written word. Conclusion: Anomia in the initial phase of Alzheimer's disease is due to problems in lexical retrieval; however, as the disease advances, in addition to lexical retrieval problems, conceptual knowledge causes naming problems. © 2017 The Author(s) Published by S. Karger AG, Basel.