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Age of Puberty in a Representative Sample of Iranian Girls Publisher Pubmed



Kashani HH1 ; Kavosh MS1 ; Keshteli AH1 ; Montazer M2 ; Rostampour N3 ; Kelishadi R4 ; Shariatnejad K5 ; Memarardestani P3 ; Hosseini SM5 ; Abdeyazdan Z3 ; Hashemipour M3, 6
Authors
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Authors Affiliations
  1. 1. Medical Students Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Biostatistics, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Department of Pediatric Endocrinology, Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan 81876-98191, Khorram Street, Iran

Source: World Journal of Pediatrics Published:2009


Abstract

Background: To obtain normal references for growth and pubertal development in a given population, assessment of pubertal stages is of great importance. This study aimed to determine the age of appearance of secondary sexual characteristics in a representative sample of Iranian girls. Methods: This cross-sectional study was conducted during 2005-2006 in 3192 girl students, aged 6-17 years, in Isfahan, Iran. Participants were selected by multistage random cluster sampling from school students. Secondary sexual characteristics were evaluated by inspection and palpation, and were recorded according to Tanner staging. The self-reported date of menarche (if any) was recorded as well. Data were analyzed with Probit analysis based on the status quo method. Results: The median ages (10th-90th percentile) of Tanner stage 2 breast development (B2) and Tanner stage 2 pubic hair growth (PH2) were 10.14 years (8.33-11.95 years) and 10.78 years (9.09-12.48 years), respectively. The ages of the 3rd percentile for B2 and PH2 were 7.48 and 8.29 years, respectively. The median age of menarche among the 3192 girls who had experienced menarche was 12.65 years (11.18-14.11 years). Conclusions: The median age of puberty onset is 10.14 years, and the onset of puberty before 7.5 years is considered as precocious puberty in a representative sample of Iranian girls. The values obtained from the present study can provide baseline data for analysis of time trends, as well as for international comparisons. © Children's Hospital, Zhejiang University School of Medicine and Springer-Verlag GmbH 2009.
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