Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro

Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro

Jabari M¹ ; Asghari G¹ ; Ghanadian M¹ ; Jafari A¹ ; Yousefi H² ; Jafari R² ; Sharafi SM³ ; Darani HY²

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1. Department of Phamacagnozi, Isfahan University of Medical Sciences, Isfahan, Iran
2. Department of Parasitology, Isfahan University of Medical Sciences, Isfahan, Iran
3. Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of HerbMed Pharmacology Published:2015

Abstract

Introduction: Trichomonas vaginalis (T. vaginalis) is a protozoan parasite causing trichomoniasis or trichomonal vaginitis. The infection is considered as non-viral sexually transmitted disease (STD). Metronidazole and Tinidazole are now the drugs of choice for the treatment of this infection. However, resistant to these drugs has also been reported. So it is necessary to search for effective alternative drugs with fewer side effects. Chaerophyllum macropodum (C. macropodum) plant have been used against some parasites. Therefore, in this study the effects of different extracts of this plant on T. vaginalis in culture media have been investigated. Methods: In this experimental study hydro-ethanol extracts of C. macropodum leaves were prepared. Anti-T. vaginalis activities of the extracts were tested in concentrations of 2, 4, 8, 16, 32, 40, 50, 60, 80, 100 and 150 mg/ml following 24, 48 and 72 hours of incubation of cultured media. Results: All extract concentrations showed some degrees of growth inhibition activity on T. vaginalis. However crude extract was more efficient. Conclusion: C. macropodum showed an anti-T. vaginalis activity. More investigations are recommended to use this plant as an antiparasitic drug.

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Hossein Yousofi Darani (7)

Gholamreza Asghari (3)

Style	Citing Format
MLA	Jabari M, et al.. "Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro." Journal of HerbMed Pharmacology, vol. 4, no. 2, 2015, pp. 61-64.
APA	Jabari M, Asghari G, Ghanadian M, Jafari A, Yousefi H, Jafari R, Sharafi SM, Darani HY (2015). Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro. Journal of HerbMed Pharmacology, 4(2), 61-64.
Chicago	Jabari M, Asghari G, Ghanadian M, Jafari A, Yousefi H, Jafari R, Sharafi SM, Darani HY. "Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro." Journal of HerbMed Pharmacology 4, no. 2 (2015): 61-64.
Harvard	Jabari M et al. (2015) 'Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro', Journal of HerbMed Pharmacology, 4(2), pp. 61-64.
Vancouver	Jabari M, Asghari G, Ghanadian M, Jafari A, Yousefi H, Jafari R, et al.. Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro. Journal of HerbMed Pharmacology. 2015;4(2):61-64.
BibTex	@article{ author = {Jabari M and Asghari G and Ghanadian M and Jafari A and Yousefi H and Jafari R and Sharafi SM and Darani HY}, title = {Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro}, journal = {Journal of HerbMed Pharmacology}, volume = {4}, number = {2}, pages = {61-64}, year = {2015} }
RIS	TY - JOUR AU - Jabari M AU - Asghari G AU - Ghanadian M AU - Jafari A AU - Yousefi H AU - Jafari R AU - Sharafi SM AU - Darani HY TI - Effect of Chaerophyllum Macropodum Extracts on Trichomonas Vaginalis in Vitro JO - Journal of HerbMed Pharmacology VL - 4 IS - 2 SP - 61 EP - 64 PY - 2015 ER -

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