Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis

Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis Publisher Pubmed

Ansari B^{1, 2, 3} ; Salortcampana E^{1, 4, 5} ; Ogier A² ; Le Troter Phd A² ; De Sainte Marie B¹ ; Guye M² ; Delmont E^{1, 5} ; Grapperon AM^{1, 5} ; Verschueren A^{1, 5} ; Bendahan D² ; Attarian S^{1, 4, 5}

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1. Centre de reference PACA Reunion Rhone Alpes, La Timone University Hospital, Aix-Marseille University, Marseille, United States
2. Aix-Marseille University, Centre de Resonance Magnetique Biologique et Medicale, UMR CNRS, Marseille, France
3. Isfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
4. INSERM, GMGF, Aix Marseille University, Marseille, France
5. FILNEMUS, United States

Source: Muscle and Nerve Published:2020

Abstract

Background: Fat infiltration in individual muscles of sporadic inclusion body myositis (sIBM) patients has rarely been assessed. Methods: Sixteen sIBM patients were assessed using MRI of the thighs and lower legs (LL). The severity of fat infiltration, proximal-to-distal and side asymmetries, and the correlations with clinical and functional parameters were investigated. Results: All the patients had fat-infiltrated muscles, and thighs were more severely affected than LL. A proximal-to-distal gradient of fat infiltration was mainly observed for adductors, quadriceps, sartorius, and medial gastrocnemius muscles. A strong negative correlation was observed between the whole muscle fat fraction in the thighs and LL and the Inclusion Body Myositis Functional Rating Scale and Medical Research Council scores for the lower limbs. Conclusions: Fat infiltration in individual muscles of sIBM patients is heterogeneous in terms of proximal-to-distal gradient and severity was correlated with clinical scores. These results should be considered for both natural history investigation and clinical trials. © 2020 Wiley Periodicals, Inc.

Style	Citing Format
MLA	Ansari B, et al.. "Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis." Muscle and Nerve, vol. 61, no. 4, 2020, pp. 496-503.
APA	Ansari B, Salortcampana E, Ogier A, Le Troter Phd A, De Sainte Marie B, Guye M, Delmont E, Grapperon AM, Verschueren A, Bendahan D, Attarian S (2020). Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis. Muscle and Nerve, 61(4), 496-503.
Chicago	Ansari B, Salortcampana E, Ogier A, Le Troter Phd A, De Sainte Marie B, Guye M, Delmont E, et al.. "Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis." Muscle and Nerve 61, no. 4 (2020): 496-503.
Harvard	Ansari B et al. (2020) 'Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis', Muscle and Nerve, 61(4), pp. 496-503.
Vancouver	Ansari B, Salortcampana E, Ogier A, Le Troter Phd A, De Sainte Marie B, Guye M, et al.. Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis. Muscle and Nerve. 2020;61(4):496-503.
BibTex	@article{ author = {Ansari B and Salortcampana E and Ogier A and Le Troter Phd A and De Sainte Marie B and Guye M and Delmont E and Grapperon AM and Verschueren A and Bendahan D and Attarian S}, title = {Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis}, journal = {Muscle and Nerve}, volume = {61}, number = {4}, pages = {496-503}, year = {2020} }
RIS	TY - JOUR AU - Ansari B AU - Salortcampana E AU - Ogier A AU - Le Troter Phd A AU - De Sainte Marie B AU - Guye M AU - Delmont E AU - Grapperon AM AU - Verschueren A AU - Bendahan D AU - Attarian S TI - Quantitative Muscle Mri Study of Patients With Sporadic Inclusion Body Myositis JO - Muscle and Nerve VL - 61 IS - 4 SP - 496 EP - 503 PY - 2020 ER -

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