Comparative Study of Electrocardiogram Changes in Patients With Brain Tumors With Midline Shift and Without Midline Shift; [بررسی مقایس های تغییرات الکتروکاردیوگرام در بیماران با تومورهای مغزی با و بدون میدلاین شیف ت]



Zamani M¹ ; Babakhanian M² ; Heydari F¹ ; Nasresfahani M¹ ; Zarezadeh MM¹ Show Affiliations
Source: Tehran University Medical Journal Published:2022

Abstract

Background: In addition to heart disease, ECG also changes in non-heart disease which due to its similarity, can lead to misdiagnosis of heart disease in patients. ECG changes in brain lesions such as ischemic and hemorrhagic strokes, brain traumas, etc and have been studied in many articles, but the effects of brain midline shift on ECG changes have not been studied. In this study, we want to examine these changes. Methods: This is a prospective cross-sectional descriptive study. Patients with brai tumors who were referred to Al-Zahra and Kashani hospitals in Isfahan from Apri 2019 to March 2021 were selected. Patients with a history of heart disease, patient receiving medications that cause ECG changes, patients with ECG changes due to non cardiac and cerebral causes, and individuals under 15 years of age were not included i the study. Patients whose ECG changes were due to electrolyte disturbances or acut heart problems were also excluded from the study. After obtaining informed consen from patients, a CT scan or brain MRI was taken and patients were divided into tw groups with and without midline shift. Then the ECG was taken and ECG changes (T wave, ST segment, QTc Interval, QRS prolongation) were compared in two groups o brain tumors with and without midline shift. Results: 136 patients were included in the study. Of these, 69 patients were in th without midline shift group and 67 patients were in the midline shift group. In th midline shift group, 3% of patients had ST segment changes and 23.9% had T wav changes, which were 1.4% and 10.1% in the without midline shift group, respectively The mean QTc Interval in the two groups without and with midline shift was 338.26 (28.438) and 388.66 (37.855), respectively, and the mean QRS in the without midlin shift group was 86.09 (88.9.88) ms and in the midline shift group was 94.63 (±12.83 ms. Conclusion: Brain midline shifts can cause QRS widening, QTc interval prolongation and T-wave changes in patients' ECGs. © 2022 Zamani et al. Tehran University of Medical Sciences. Published by Tehran University of Medical Sciences.