Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Prevalence of Nonalcoholic Fatty Liver Disease in Children With Renal Failure Underwent Treatment With Dialysis Publisher



Madihi Y1 ; Tavakoli R2 ; Riahinezhad M3 ; Mostofizadeh N4 ; Mehrkash M1 ; Rostampour N4 ; Hovsepian S3, 5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Pediatric Nephrology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Metabolic Liver Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Imam Hossein Children's Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Source: International Journal of Preventive Medicine Published:2022


Abstract

Background: In this study, we aimed to investigate the prevalence of nonalcoholic fatty liver disease (NAFLD) in children with renal failure under treatment with dialysis and its association with biochemical measurements. Methods: In this cross-sectional study, children aged less than 18 years with chronic kidney disease (CKD) who were under treatment with dialysis at least 3 months ago were enrolled. To evaluate fatty liver in those patients who had no recent liver ultrasonography (last 6 months), liver ultrasonography was performed. The characteristics of patients with renal failure with and without NAFLD based on the ultrasonographic evaluation were compared. The association between NAFLD and the studied variables was evaluated. Results: In this study, 39 children (31 males and 8 females) with renal failure who underwent treatment with dialysis were included. From the studied population, six (19.4%) had NAFLD based on ultrasonographic evaluation. There were no differences between renal failure patients with and without NAFLD regarding the biochemical and anthropometric characteristics (P > 0.0). Conclusions: The prevalence of NAFLD in our studied children with renal failure who underwent treatment with dialysis was like the general population and it was not associated with the biochemical and anthropometric characteristics of the patients. Given the importance of NAFLD in renal failure patients as well as its subtle nature, it is recommended to screen patients with CKD for NAFLD. © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
Related Docs
View other Related Docs
1. Intake of Nutrients, Fiber, and Sugar in Patients With Nonalcoholic Fatty Liver Disease in Comparison to Healthy Individuals, International Journal of Preventive Medicine (2016)
2. Chronic Kidney Disease in Iran: First Report of the National Registry in Children and Adolescences, Urology Journal (2021)
3. Do Kidney Sizes in Ultrasonography Correlate to Glomerular Filtration Rate in Healthy Children?, Australasian Radiology (2007)
4. Doppler Perfusion Index in Adolescents With Nonalcoholic Fatty Liver Disease, Immunopathologia Persa (2021)
5. Sonographic Fatty Liver in Overweight and Obese Children, a Cross Sectional Study in Isfahan, Endokrynologia Polska (2009)
6. Hepatic Artery and Portal Vein Doppler Indexes in Non-Alcoholic Fatty Liver Disease Before and After Treatment to Prevent Unnecessary Health Care Costs, International Journal of Preventive Medicine (2014)
7. Comparison of the Effect of Omega-3 Vs. Mct Supplementation on Iron-Related Indices in Patients Undergoing Dialysis, Biological Trace Element Research (2024)
8. Obesity and Air Pollution: Global Risk Factors for Pediatric Non-Alcoholic Fatty Liver Disease, Hepatitis Monthly (2011)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (16)
Alaleh Gheissari (13)
Other Related Docs
9. Factors Associated With Insulin Resistance and Non-Alcoholic Fatty Liver Disease Among Youths, Atherosclerosis (2009)
10. First-Degree Relatives of Patients With Type 2 Diabetes Mellitus and Risk of Non-Alcoholic Fatty Liver Disease, Review of Diabetic Studies (2007)
11. Metabolic Disorders in Patients With Nephrolithiasis in Iran, Iranian Journal of Kidney Diseases (2022)
12. Glomerular Hyperfiltration As Predictor of Cardiometabolic Risk Factors Among Children and Adolescents: The Childhood and Adolescence Surveillance and Prevention of Adult⇑V Study, International Journal of Preventive Medicine (2018)
13. Determination of Frequency of Diabetes and Pre-Diabetes in Patients With Nonalcoholic Fatty Liver Disease and Comparison With a Control Group, Journal of Isfahan Medical School (2016)
14. Prevalence of Diabetic Neuropathy in Nonalcoholic Fatty Liver Disease (Nafld) Patients: A Systematic Review and Meta-Analysis, Neurology Asia (2024)
15. Diet Macronutrients Composition in Nonalcoholic Fatty Liver Disease: A Review on the Related Documents, Hepatitis Monthly (2014)
16. The Association of the Healthy Food Diversity Index With the Risk of Non-Alcoholic Fatty Liver Disease Among the Adult Population, Clinical Nutrition ESPEN (2024)
17. Dietary Quality Indices and Biochemical Parameters Among Patients With Non Alcoholic Fatty Liver Disease (Nafld), Hepatitis Monthly (2013)
18. Pruritus Features in Children With End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study, International Journal of Pediatrics (United Kingdom) (2021)
19. Metabolic Syndrome and Nonalcoholic Fatty Liver Disease: Nutritional Approach for Prevention, Journal of Isfahan Medical School (2013)
20. Acute Kidney Injury: A Pediatric Experience Over 10 Years at a Tertiary Care Center, Journal of Nephropathology (2012)
21. Non-Alcoholic Steatohepatitis in a Sample of Iranian Adult Population: Age Is a Risk Factor, International Journal of Preventive Medicine (2011)
22. The Effect of a Mediterranean Diet on Metabolic Parameters in Patients With Non-Alcoholic Fatty Liver Disease: A Systematic Review of Randomized Controlled Trials, Clinical Nutrition ESPEN (2020)
23. Effects of the Mixture of Melissa Officinalis L., Cinnamomum Zeylanicutn and Urtica Dioica on Hepatic Enzymes Activity in Patients With Nonalcoholic Fatty Liver Disease, International Journal of Pharmacology (2012)
24. Treatment of Non-Alcoholic Fatty Liver Disease With Curcumin: A Randomized Placebo-Controlled Trial, Phytotherapy Research (2016)
25. The Quality of Life in Children With Nephritic Syndrome in Isfahan, Iran, Journal of Isfahan Medical School (2013)
26. The Effect of Synbiotic Supplementation on Body Composition and Lipid Profile in Patients With Nafld: A Randomized, Double Blind, Placebo-Controlled Clinical Trial Study, Iranian Red Crescent Medical Journal (2017)
27. Risk Score Model for Predicting Sonographic Non-Alcoholic Fatty Liver Disease in Children and Adolescents, Iranian Journal of Pediatrics (2011)
28. Comparison of the Performance of the Updated Schwartz, Combined Schwartz and the Grubb Glomerular Filtration Rate Equations in a General Pediatric Population., Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2014)
29. The Effect of Vitamin D Supplementation on Insulin Resistance in Patients With Nonalcoholic Fatty Liver, Journal of Isfahan Medical School (2015)
30. Direct Association Between High Fat Dietary Pattern and Risk of Being in the Higher Stages of Chronic Kidney Disease, International Journal for Vitamin and Nutrition Research (2019)
31. Chronic Kidney Disease in Children: A Report From a Tertiary Care Center Over 11 Years, Journal of Nephropathology (2012)
32. Renal Cortical Thickness in Adults With Normal Renal Function Measured by Ultrasonography, Iranian Journal of Radiology (2008)
33. Association Between Adherence to the Mediterranean Diet and Renal Function Biomarkers and Cardiovascular Risk Factors Among Diabetic Patients With Nephropathy, Clinical Nutrition ESPEN (2020)
34. The Association Between Major Dietary Patterns With the Risk of Non-Alcoholic Fatty Liver Disease, Oxidative Stress and Metabolic Parameters: A Case–Control Study, Journal of Diabetes and Metabolic Disorders (2022)
35. Curcumin Supplementation Effect on Liver Enzymes in Patients With Nonalcoholic Fatty Liver Disease: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials, Nutrition reviews (2025)
36. Prognostic Role of Neutrophil to Lymphocyte Ratio in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis, Canadian Journal of Gastroenterology and Hepatology (2022)
37. Improving Data Adequacy of Ultrasonography Reports for Non-Alcoholic Fatty Liver Disease (Nafld) Through a National Structured Template, Acta Radiologica (2023)
38. Diagnostic Performance of Ultrasonography in Detecting Fatty Liver Disease in Comparison With Fibroscan in People Suspected of Fatty Liver, Advanced Biomedical Research (2019)
39. The Ratio of Dietary Diversity Score Versus Energy Density in Relation to Anthropometric and Biochemical Variables Among Patients With Chronic Kidney Diseases, Progress in Nutrition (2019)
40. Comparing the Urinary Value of N-Acetyl-Β-D-Glucosaminidase (Nag) and Β2-Microglobulinuria (Β2m) in Acute Kidney Damage in Children, Journal of Isfahan Medical School (2013)
41. Effect of a Moderately Carbohydrate-Restricted Diet on Liver Enzymes, Steatosis and Fibrosis in Normal-Weight Individuals With Non-Alcoholic Fatty Liver Disease: Study Protocol for a Parallel Randomised Controlled Clinical Trial, BMJ Open (2023)
42. The Effect of Symbiotic Supplementation on Liver Enzymes, C‑Reactive Protein and Ultrasound Findings in Patients With Non‑Alcoholic Fatty Liver Disease: A Clinical Trial, International Journal of Preventive Medicine (2016)
43. Comparison of Three Diet Quality Indices for Patients With Chronic Kidney Disease, Archives of Iranian Medicine (2017)
44. Is Ckd Screening Program Necessary in Developing Countries?, Iranian Journal of Kidney Diseases (2023)
45. Evaluation of Lipid Profile Changes in Patients During One Year After the Onset of Peritoneal Dialysis, Journal of Isfahan Medical School (2020)
46. Association of Neutrophil Gelatinase Associated Lipocalin and Cystatin-C With Kidney Function in Children With Nephrotic Syndrome, International Journal of Preventive Medicine (2013)
47. Adaptation of Clinical Practice Guideline for Assessment of Liver Fibrosis in Patients With Non Alcoholic Fatty Liver Disease in Isfahan Province, International Journal of Preventive Medicine (2024)
48. Vitamin E + Ursodeoxycholic Acid (Udca) Versus Vitamin E for the Treatment of Non-Alcoholic Steatohepatitis (Nash), Journal of Isfahan Medical School (2010)
49. Evaluation of Hyponatremia Among Cirrhotic Patients in Shariati Hospital, Isfahan, Iran, Polish Annals of Medicine (2018)
50. The Effects of Low Carbohydrate Diets on Liver Function Tests in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Clinical Trials, Journal of Research in Medical Sciences (2016)