Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Seroepidemiology of Toxoplasma Gondii Infection in Pregnant Women in West Iran: Determined by Elisa and Pcr Analysis Publisher



Ahmadpour GR1 ; Ezatpour B2 ; Hadighi R1 ; Oormazdi H1 ; Akhlaghi L1 ; Tabatabaei F1 ; Azami M3 ; Nejad MM2 ; Mahmoudvand H2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Razi Herbal Medicines Research Center, Department of Medical Parasitology and Mycology, Lorestan University of Medical Sciences, Khorramabad, Iran
  3. 3. Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Parasitic Diseases Published:2017


Abstract

Congenital toxoplasmosis can lead to severe damage for the fetus and newborn. Considering that the seroepidemiology of Toxoplasma infection in the pregnant women is poorly studied in west of Iran, the main objective of this study was to estimate the seroprevalence and potential risk factors for congenital toxoplasmosis in Delfan, Iran. In this cross-sectional study, the serum samples obtained from pregnant women who were referred to health centers for routine monitoring of the pregnancy. Totally, 264 sera were screened for IgG and IgM anti-T. gondii antibodies by enzyme linked immunosorbent assay method. All women with IgM anti-T. gondii positive checked by RT-PCR and confirmed. In addition, structured questionnaires were used to obtain information on risk factors for T. gondii infection. Anti-Toxoplasma IgG and IgM were positive in 66 (25 %) and 15 (5.7 %) respectively. Seropositive subjects were more frequently seen in those with >30 years old compared to younger women (<25 years old) (p < 0.001). No significant relationship was found between the seroprevalence of T. gondii infection and level of education, and gestational age (p > 0.05), while there was statistical difference between the infection with cat exposure, consumption of raw/undercooked meat, eating raw or uncooked eggs, consumption of unwashed vegetables and drinking unpasteurized milk (p < 0.001). In the present study, it was found that T. gondii infection was present among pregnant women in west of Iran. Therefore, it is suggested to provide health education for preventing primary infection during pregnancy and subsequently congenital toxoplasmosis in the pregnant women. © 2016, Indian Society for Parasitology.
Related Docs
View other Related Docs
1. Seroprevalence of Toxoplasmosis in Mentally Retarded Patients in Iranian Rehabilitation Centers, Journal of Parasitic Diseases (2015)
2. Prevalence of Anti-Toxoplasma Gondii Antibodies in Young Iranians: The Caspian Iii Study, Archives of Pediatric Infectious Diseases (2018)
3. Toxoplasma Serology Status and Risk of Miscarriage, a Case-Control Study Among Women With a History of Spontaneous Abortion, International Journal of Fertility and Sterility (2019)
4. Seroprevalence of Toxoplasma Gondii and Toxocara Spp. Infections Among Pregnant Women With and Without Previous Abortions in the West of Iran, Journal of Obstetrics and Gynaecology Research (2020)
5. Prevalence of Toxoplasmosis and Related Risk Factors Among Humans Referred to Main Laboratories of Urmia City, North West of Iran, 2013, Journal of Parasitic Diseases (2016)
6. A Large-Scale Study on the Seroprevalence of Toxoplasma Gondii Infection in Humans in Iran, Folia Parasitologica (2023)
7. Seroepidemiology of Toxoplasma Gondii Infection in Isfahan Province, Central Iran: A Population Based Study, Journal of Research in Medical Sciences (2011)
8. Seroprevalence of Toxoplasmosis in Kermanshah City, West of Iran, Annals of Parasitology (2021)
Experts (# of related papers)
View all Related Experts
Seyed Hossein Hejazi (9)
Hossein Yousofi Darani (6)
Other Related Docs
9. Study of Serological Toxoplasmosis and Risk Factors Associated With Infection in Women Referred to Labs of Northern Tehran, Iran, Journal of Isfahan Medical School (2013)
10. Detection of Toxoplasma Gondi in Acute and Chronic Phases of Infection in Immunocompromised Patients and Pregnant Women With Real-Time Pcr Assay Using Taqman Fluorescent Probe, Iranian Journal of Parasitology (2018)
11. Frequency of Sero-Positivity in Household Members of the Patients With Positive Toxoplasma Serology; [Frecuencia De Seropositividad En Los Miembros De Hogares De Pacientes Con Serologia Positiva Para Toxoplasma], Revista Espanola de Quimioterapia (2018)
12. The Seroprevalence of Anti-Toxoplasma Gondii Igg and Igm Antibodies in Serum Samples Referred to Educational Hospitals of Abadan, Journal of Isfahan Medical School (2022)
13. Toxoplasmosis and Symptoms Severity in Patients With Covid-19 in Referral Centers in Northern Iran, Journal of Parasitic Diseases (2023)
14. High Occurrence of Toxoplasma Gondii Infection Among Blood Donors in Ardabil Province As Main Focus of Zoonotic Visceral Leishmaniosis, Northwestern Iran, Annals of Parasitology (2021)
15. Comparison of the Re-529 Sequence and B1 Gene for Toxoplasma Gondii Detection in Blood Samples of the At-Risk Seropositive Cases Using Uracil Dna Glycosylase Supplemented Loop-Mediated Isothermal Amplification (Udg-Lamp) Assay, Microbial Pathogenesis (2020)
16. Detection of Toxoplasma Parasitemia by Pcr: Does It Correlate With Igg and Igm Antibody Titers?, Iranian Journal of Immunology (2006)
17. Evaluation of Toxoplasma Gondii Infection in Western Iran: Seroepidemiology and Risk Factors Analysis, Tropical Medicine and Health (2020)
18. Prevalence of Toxoplasma Gondii in Hiv-Infected Individuals in Iran: A Systematic Review and Meta-Analysis, Current HIV Research (2023)
19. Evaluation of Antinuclear Antibodies in Pregnant Women With Abortion With Toxocariasis and Toxoplasmosis in Iran; [Iran’Da Toksokariyaz Ve Toksoplazmozlu Dusuk Yapan Gebelerde Antinukleer Antikorlarin Degerlendirilmesi], Turk Hijyen ve Deneysel Biyoloji Dergisi (2022)
20. Prevalence of Toxoplasma Infection in Veterinary Laboratory Sciences Students Comparing to Ordinary People: A Case–Control Study, Journal of Parasitic Diseases (2016)
21. Sero-Molecular Prevalence of Toxoplasmosis in Hemodialysis and Peritoneal Dialysis Patients in Markazi Province, Iran, Tropical Medicine and Health (2025)
22. Prevalence of Toxoplasma Gondii and the Level of Il8 in Patients With Celiac Disease, Koomesh (2016)
23. Serological Evaluation of Anti-Toxoplasma Gondii Antibodies in Patients With Acute Leukemia and Lymphoma Through Chemotherapy, Iranian Journal of Parasitology (2020)
24. A Systematic Review of Toxoplasma Gondii Antigens to Find the Best Vaccine Candidates for Immunization, Microbial Pathogenesis (2019)
25. Toxoplasmosis in Iranian Abortion Cases With Appendectomy, Journal of Applied Biological Sciences (2012)
26. Low Titer of Antibody Against Toxoplasma Gondii May Be Related to Resistant to Cancer, Journal of Cancer Research and Therapeutics (2015)
27. Human Anti-Toxoplasma Antibodies Attach Strongly to Breast Cancer Cells, International Journal of Cancer Management (2023)
28. Cloning, Expression and Characterization of Toxoplasma Gondii P35 Protein in E. Coli, Yakhteh (2006)
29. The Prevalence Rate of Infection to Toxoplasma Gondii in Domestic and Industrial Breeding Poultry in Isfahan City, Iran, 2020, Journal of Isfahan Medical School (2021)
30. The Probable Association Between Chronic Toxoplasma Gondii Infection and Type 1 and Type 2 Diabetes Mellitus: A Case-Control Study, Interdisciplinary Perspectives on Infectious Diseases (2021)
31. Utility of Blood As the Clinical Specimen for the Diagnosis of Ocular Toxoplasmosis Using Uracil Dna Glycosylase-Supplemented Loop-Mediated Isothermal Amplification and Real-Time Polymerase Chain Reaction Assays Based on Rep-529 Sequence and B1 Gene, BMC Infectious Diseases (2022)
32. Seroprevalence of Toxoplasma Infection in Individuals Occupationally Exposed to Livestock and Raw Meat: A Case–Control Study, Veterinary Medicine and Science (2023)
33. Evaluation of Th17 Immune Responses of Recombinant Dna Vaccine Encoding Gra14 and Rop13 Genes Against Toxoplasma Gondii in Balb/C Mice, Infection, Genetics and Evolution (2021)
34. Risk Factors and Prevalence of Toxocariasis in Pregnant Women and Diabetic Patients Compared to Healthy Adults in Ilam Province, Western Iran, EXCLI Journal (2018)
35. Contributions of Hla Haplotypes, Il8 Level and Toxoplasma Gondii Infection in Defining Celiac Disease's Phenotypes, BMC Gastroenterology (2018)
36. Insights Into the Biochemical Features and Immunogenic Epitopes of Common Bradyzoite Markers of the Ubiquitous Toxoplasma Gondii, Infection, Genetics and Evolution (2021)
37. In Vitro and in Vivo Anti-Toxoplasma Activity of Dracocephalum Kotschyi Essential Oil, Food Science and Nutrition (2021)
38. Toxocara Seroprevalence and Associated Risk Factors Among Ilam Children, West of Iran, Archives of Pediatric Infectious Diseases (2019)
39. Knocking Down the Expression of the Molecular Motors, Myosin A, C and F Genes in Toxoplasma Gondii to Decrease the Parasite Virulence, Experimental Parasitology (2023)
40. Anti-Toxoplasma Gondii Antibodies Attach to Mouse Cancer Cell Lines But Not Normal Mouse Lymphocytes, Biomedical Reports (2019)
41. Comparison of Eight Cell-Free Media for Maintenance of Toxoplasma Gondii Tachyzoites, Iranian Journal of Parasitology (2016)
42. Frequency of Blood-Tissue Parasitic Infections in Patients With Multiple Sclerosis, As Compared to Their Family Members, International Journal of Preventive Medicine (2014)
43. Toxoplasma Gondii Tyrosine-Rich Oocyst Wall Protein: A Closer Look Through an in Silico Prism, BioMed Research International (2021)
44. A Systematic Review on the Role of Gra Proteins of Toxoplasma Gondii in Host Immunization, Journal of Microbiological Methods (2019)
45. Seroepidemiology of Toxocariasis in Children (5-15 Yr Old) Referred to the Pediatric Clinic of Imam Hossein Hospital, Isfahan, Iran, Iranian Journal of Parasitology (2015)
46. The Gene Expression Level of Ifn-Γr1 and Ifn-Γr2 in a Murine Model Treated With Toxoplasma Gondii and Its Products, Gastroenterology and Hepatology from Bed to Bench (2016)
47. Seroprevalence of Toxocaracanis in Asthmatic Children and Its Relation to the Severity of Diseases - a Case-Control Study, Medical archives (Sarajevo, Bosnia and Herzegovina) (2018)
48. Association Between T3, T4, and Tsh Hormones Proportion and Toxoplasma Gondii Anti-Igg Seroprevalence in Patients Suffering From Clinical and Drug-Controlled Thyroid Dysfunctions in Southeastern Iran; [Guneydogu Iran'da Klinik Ve Ilac Kontrollu Tiroid Fonksiyon Bozuklugu Olan Hastalarda T3, T4 Ve Tsh Hormonlari Orani Ile Toxoplasma Gondii Anti-Igg Seroprevalansi Arasindaki Iliski], Turk Hijyen ve Deneysel Biyoloji Dergisi (2021)