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Dietary Inflammatory Index and the Risk of Frailty Among Older Adults: A Systematic Review and Meta-Analysis Publisher Pubmed



Moradi S1 ; Hadi A2 ; Mohammadi H1 ; Asbaghi O3 ; Zobeiri M4 ; Marx W5 ; Entezari MH1
Authors
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Authors Affiliations
  1. 1. Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Iran
  2. 2. Halal Research Center of IRI, FDA, Tehran, Iran
  3. 3. Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
  4. 4. Department of Internal Medicine, School of Medicine, Kermanshah University of Medical Sciences, Iran
  5. 5. School of Medicine, Barwon Health, IMPACT (the Institute for Mental and Physical Health and ClinicalTranslation), Food Mood Centre, Deakin University, Melbourne, VIC, Australia

Source: Research on Aging Published:2021


Abstract

A systematic review and meta-analysis was conducted to comprehensively examine the association between Dietary Inflammatory Index (DII®) score and risk of frailty. Frailty risk were available from five studies comprising 13,908 older adults. Furthermore, frailty related parameters were extacted from two studies with 7,539 individuals. A pooled adjusted odds ratio analysis indicated that there was an association between DII® score and frailty risk (OR = 1.24, 95%CI: 1.6–1.33, P < 0.001, I2 = 0.0%). The results of frailty related parameters demonstrated that DII® score was associated with weakness risk (OR = 1.12, 95%CI: 1.05–1.19, P = 0.014, I2 = 0.0%), but not other frailty-related parameters including exhaustion, low BMI or low physical activity. The results of this meta-analysis suggest that older adults who exhibit higher DII® scores have an increased frailty risk. Further prospective cohort studies with longer follow-up periods, are needed to support this possible association between DII® score and frailty risk. © The Author(s) 2020.
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