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The Effect of Consuming Nuts on Cognitive Function: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Publisher



Moabedi M1 ; Aliakbari M1 ; Erfanian S2 ; Jibril AT3 ; Milajerdi A4
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Authors Affiliations
  1. 1. Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran
  2. 2. Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran

Source: Frontiers in Nutrition Published:2024


Abstract

Background: Results from clinical trials investigating the effect of nuts consumption on cognition are conflicting. We decided to conduct the current meta-analysis to summarize all available evidence on the effect of consuming nuts on cognition scores. Methods: We conducted a comprehensive search in the online databases using relevant keywords up to June 2024. We included all the published Randomized clinical trials (RCTs) investigating the effect of nuts, compared to control, on cognition scores. Results: Overall, 5 trials were included with a total sample size of 928 adults. Based on 6 effect sizes from these 5 trials, we did not find a significant effect of nuts on cognition function [Standardized Mean Difference (SMD): 0.27, 95% CI: −0.65 to 1.19, p = 0.57]. Conclusion: Our review could not find a significant effect of nuts on cognition function. Future high-quality RCTs with larger sample sizes should be conducted to shed light on the impact of nuts on cognition. Copyright © 2024 Moabedi, Aliakbari, Erfanian, Jibril and Milajerdi.
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