Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Relationship Between Storage Time of Blood Products and Morbidity and Mortality After Coronary Artery Bypass Graft Surgery



Bagheri K1 ; Talebi S2 ; Najarzadegan M2 ; Aghadavoudi O1 ; Akbari M2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Anesthesiology and Critical Care, School of Medicine and Anesthesiology and Critical Care Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2012

Abstract

Background: There are some paradoxical results about complications of long time stored blood transfusion. In this research we surveyed these clinical complications and relationship between morbidity and mortality with time of storage. Methods: This cross-sectional study was preformed on 100 coronary artery bypass graft (CABG) candidates in Chamran Hospital, Iran, in 2010. We compared the complications of using old blood (with storage time more than 14 days) and fresh blood (with storage time less than 14 days). Renal complications were assessed by blood urea nitrogen (BUN) and creatine (Cr) levels. In addition, liver complications were evaluated based on prothrombin time (PT) and partial thromboplastin time (PTT). We also measured ICU stay, ventilation time and mortality in the two groups. Findings: Renal complications, bleeding after surgery, raised coagulation test values such as PTT were significantly more prevalent in old blood takers (P = 0.001, 0.003, and 0.007, respectively). However, there were no significant differences in hemoglobin (P = 0.001), hematocrit (P = 0.001), platelet count (P = 0.001) and mortality between the two groups. Conclusion: In accordance with previous research, the results of this study showed blood storage more than 14 days to increase complications after surgery. Therefore, fresh blood transfusion is recommended for CABG patients.
Related Docs
View other Related Docs
1. Prognostic Value of Procalcitonin for Morbidity and Mortality in Patients After Cardiac Surgery, Cardiology Research and Practice (2021)
2. Evaluation of Changes in Platelet Level and Influenced Factors in Patients With Thrombocytopenia, Journal of Isfahan Medical School (2018)
3. A Comparative Study of Stored Arterial Versus Venous Blood Collected Using the Acute Normovolemic Hemodilution Method in Coronary Artery Bypass Grafting Patients in Iran, Acute and Critical Care (2023)
4. Continuous Infusion Versus Intermittent Intravenous Heparin Injection Effect on Coagulation State After Peripheral Vascular Surgery, Journal of Isfahan Medical School (2011)
5. Comparison of the Relationship Between Preoperative Hemoglobin Level and Acute Renal Failure in Patients Undergoing Noncardiac Surgery, Journal of Isfahan Medical School (2017)
6. Effect of Different Dosages of Nitroglycerin Infusion on Arterial Blood Gas Tensions in Patients Undergoing On- Pump Coronary Artery Bypass Graft Surgery, Journal of Research in Medical Sciences (2012)
7. Does Topical Tranexamic Acid Reduce Postcoronary Artery Bypass Graft Bleeding?, Journal of Research in Medical Sciences (2018)
8. A Comparison of the Clinical Outcomes of Minimum and Maximum Hematocrit Levels During Cardiopulmonary Bypass (Cpb) in Low‑Risk Patients Undergoing Coronary Artery Bypass Graft Surgery (Cabg): A Cross‑Sectional Study, Advanced Biomedical Research (2024)
Experts (# of related papers)
View all Related Experts
Gholamreza Massoumi (6)
Babak Alikiaii (4)
Other Related Docs
9. Comparative Evaluation of the Effects of Tranexamic Acid and Low-Dose Aprotinin on Post-Valvular Heart Surgery Bleeding and Allogenic Transfusion, Interactive Cardiovascular and Thoracic Surgery (2012)
10. The Effects of Mean Arterial Pressure During Cardiopulmonary Bypass on Clinical and Paraclinical Parameters During and After Coronary Artery Bypass Graft Surgery, Journal of Isfahan Medical School (2012)
11. Efficacy and Safety of Apixaban for the Prevention of Thrombosis in Arteriovenous Grafts, European Journal of Translational Myology (2024)
12. Efficacy of Epsilon Aminocaproic Acid Versus Placebo in Coronary Artery Bypass Graft: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Current Treatment Options in Cardiovascular Medicine (2024)
13. Pattern of Maximum Demand Blood in Cardiac Surgeries in Shahid Chamran Hospital, Isfahan, Iran, During 2011-2014, Journal of Isfahan Medical School (2018)
14. The Association Between Blood Coagulation Parameters and Glasgow Coma Scale in Patients With Head Trauma Admitted to Intensive Care Unit, Journal of Isfahan Medical School (2018)
15. Comparing the Effects of Hydroxy Ethyl Starch 6% and Gelatin As Replacement for Prime During Coronary Artery Bypass Graft Surgery, Journal of Isfahan Medical School (2013)
16. Appropriate Blood Component Therapy Can Reduce Postcardiac Surgery Acute Kidney Injury Through Packed Cell Transfusion Reduction, Journal of Research in Medical Sciences (2017)
17. The Association Between Serum Lactate Level and Post Cabg Complications in Cardiac Patients, Journal of Isfahan Medical School (2011)
18. Evaluation of Platelet Elevation After Injection in Patients Over 40 Years of Age Admitted Hospital; a Retrospective Study, Journal of Isfahan Medical School (2017)
19. Does Tunneling the Temporary Vascular Access Extend Its Lifetime?, Journal of Research in Medical Sciences (2006)
20. Changes in the Hemoglobin Level After One Unit of Packed Red Blood Cell Transfusion in Intensive Care Unit Patients, Journal of Research in Medical Sciences (2018)
21. Evaluation of Platelet Elevation Following Injection of a Platelet Unit in Patients Admitted to the Intensive Care Unit, Journal of Isfahan Medical School (2018)
22. The Effect of N-Acetylcysteine in Prime Solution on Preventing Renal Failure During Cardiopulmonary Bypass Surgery, Journal of Isfahan Medical School (2021)
23. Comparing the Hemodynamic Changes During and After Coronary Artery Bypass Graft Surgery Under General Anesthesia With Propofol and Isoflurane, Journal of Isfahan Medical School (2015)
24. The Relation Between the Mean Time Interval of Opening of Aortic Cross Clamp to the End of Cardiopulmonary Bypass With Surgical Results of Patient After Coronary Artery Bypass Grafting Surgery, Journal of Isfahan Medical School (2017)
25. Comparative Study of Clinical Outcomes of Methylprednisolone and Dexamethasone in Prime Solution During Cardiopulmonary Pump After Coronary Artery Bypass Grafting, Journal of Cellular and Molecular Anesthesia (2021)
26. Comparing the Efficacy of Synthetic Fibrinogen Plus Albumin to Fresh Frozen Plasma in the Prevention of Coagulation Disorders in Pediatric Heart Surgery, Journal of Isfahan Medical School (2016)
27. Evaluating the Relative Frequency and Predicting Factors of Acute Renal Failure Following Coronary Artery Bypass Grafting, ARYA Atherosclerosis (2013)
28. Evaluation of Plasma Fibrinogen Levels Before and After Coronary Artery Bypass Graft Surgery and Its Association With the Need for Blood Products, Advanced Biomedical Research (2022)
29. The Effect of Oral Levothyroxine on Bleeding and Need for Inotropic Agents in Patients Undergoing Coronary Artery Bypass Graft, Journal of Isfahan Medical School (2017)
30. Impact of Preoperative Clopidogrel Administration on Perioperative Blood Loss and Transfusion Requirements in Patients Undergoing Coronary Artery Bypass Graft Surgery, Journal of Isfahan Medical School (2014)
31. Prevalence of Coagulopathy and Related Risk Factors in Patients With Trauma Hospitalized in Intensive Care Units of Alzahra Hospital, Isfahan, Iran, During 2013-2016, Journal of Isfahan Medical School (2017)