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Cost-Effectiveness of Colorectal Cancer Screening Strategies: A Systematic Review Publisher Pubmed



Gheysariyeha F1 ; Rahimi F2 ; Tabesh E3 ; Hemami MR4 ; Adibi P3 ; Rezayatmand R5
Authors
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Authors Affiliations
  1. 1. Department of Health Economics, School of Management and Medical Information Sciences Isfahan University of Medical Science, Isfahan, Iran
  2. 2. Pharmacoeconomics and Pharma Management, Research Health Management and Economics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Gastroenterology and Hepatology, Isfahan Gastroenterology and Hepatology Research Center (IGHRC), Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Epidemiology, CEO Toward Evidence, Glasgow, Glasgow, United Kingdom
  5. 5. Health Economics, Health Management and Economics Research Center Isfahan University of Medical Sciences, Isfahan, Iran

Source: European Journal of Cancer Care Published:2022


Abstract

Introduction: Colorectal cancer (CRC) is the second leading cause of death worldwide and the use of CRC screening tests can reduce the incidence and mortality of the disease by early detection. This study aims to review cost-effectiveness strategies in different ages and countries, systematically. Methods: We searched ProQuest, Web of Science, Scopus, Cochrane, PubMed and Embase for related studies between 2010 and 2020. Articles that reported costs per Quality-Adjusted Life Year or Life Year Gain and Incremental Cost-Effectiveness Ratios to compare the cost-effectiveness of CRC screening strategies in the average-risk population were included in our study. Results: The search strategies identified 426 records and finally 48 articles were included in the systematic review based on included and excluded criteria. We identified seven strategies for CRC screening. Most of the strategies were performed in aged 50–75. These studies were reported by cost per Quality-Adjusted life year (QALY)/Life Year Gain (LYG) based on methods and perspectives and the ICER of comparison of two-by-two strategies. Conclusion: Most of the CRC screening strategies were cost-effective, but there was big heterogeneity between the cost-effectiveness analysis of CRC screening strategies because of different screening methods, perspectives and screening populations. So, it is important to consider this heterogeneity to compare the economic evaluation studies in this field. © 2022 John Wiley & Sons Ltd.
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