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Association of Lymphovascular Space Invasion (Lvsi) With Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study Publisher



Rafiee A1 ; Mohammadizadeh F2
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Authors Affiliations
  1. 1. Iranian Medical and Pathology Laboratory, Zahedan, Iran
  2. 2. Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Advanced Biomedical Research Published:2023


Abstract

Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI. © 2023 Medknow. All rights reserved.
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